Trial reportJournal of the American Geriatrics Society2014
Executive function processes predict mobility outcomes in older adults.
Trial report in Journal of the American Geriatrics Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05296551 (Examination of a Novel Cognitive-motor Weight-bearing Dual-task Intervention in Older Adults), which is not on this map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Examination of a Novel Cognitive-motor Weight-bearing Dual-task Intervention in Older Adults
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Frailty and Cognitive Function in Older Adults: A Systematic Review and Meta-Analysis of Cross-Sectional Studies.Neuropsychology review · 2022Pooled it
- Executive Functioning as a Predictor of Weight Loss and Physical Activity Outcomes.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2019Trial
- A smartphone "app"-delivered randomized factorial trial targeting physical activity in adults.Journal of behavioral medicine · 2017Trial
- Effects of Gait Self-Efficacy and Lower-Extremity Physical Function on Dual-Task Performance in Older Adults.BioMed research international · 2017Trial
- Exercise Mode Moderates the Relationship Between Mobility and Basal Ganglia Volume in Healthy Older Adults.Journal of the American Geriatrics Society · 2016Trial
- The Effect of Internet Use on Older Adults' Executive Function: The Chain Mediation Effect of Social Participation and Loneliness.Healthcare (Basel, Switzerland) · 2026Article
- Autistic Trait Level and Reaction Time in Older Adults: The Influence of Sex and Task upon Study Outcome.Autism in adulthood · 2026Article
- Predicting fall risk among older adults with sarcopenia in China using machine learning models: a six-year longitudinal study from CHARLS.BMC geriatrics · 2026Article
- Article
- Global Cognition and Inhibition as Predictors of Dynamic Balance in Aging Populations: A Cross-Sectional Study.Journal of clinical medicine · 2025Article
- Implications of Intra-Individual Variability in Motor Performance on Functional Mobility in Stroke Survivors.Geriatrics (Basel, Switzerland) · 2025Article
- Risk-taking behaviour and executive functions, a major component of the risk of fall factors after recent stroke.Journal of rehabilitation medicine · 2024Article
- The Bidirectional Association Between Cognitive Function and Gait Speed in Chinese Older Adults: Longitudinal Observational Study.JMIR public health and surveillance · 2023Observational
- Predictors of cognitive and physical decline: Results from the Health Aging and Body Composition Study.Frontiers in aging neuroscience · 2023Article
- Variability in objective sleep is associated with Alzheimer's pathology and cognition.Brain communications · 2023Article
- Executive and Motor Functions in Older Individuals with Cognitive Impairment.Behavioral sciences (Basel, Switzerland) · 2022Article
- Mean arterial pressure, fitness, and executive function in middle age and older adults.Cerebral circulation - cognition and behavior · 2022Article
- The Effects of Sustained Literacy Engagement on Cognition and Sentence Processing Among Older Adults.Frontiers in psychology · 2022Article
- Effects of Intermittent Hypoxia-Hyperoxia Exposure Prior to Aerobic Cycling Exercise on Physical and Cognitive Performance in Geriatric Patients-A Randomized Controlled Trial.Frontiers in physiology · 2022Article
- Health, social care and technological interventions to improve functional ability of older adults living at home: An evidence and gap map.Campbell systematic reviews · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
objectivesTo examine the relationship between performance on executive function measures and subsequent mobility outcomes in community-dwelling older adults.
designRandomized controlled clinical trial.
settingChampaign-Urbana, Illinois.
participantsCommunity-dwelling older adults (N = 179; mean age 66.4).
interventionA 12-month exercise trial with two arms: an aerobic exercise group and a stretching and strengthening group. MEASUREMENTS: Established cognitive tests of executive function (flanker task, task switching, and a dual-task paradigm) and the Wisconsin card sort test. Mobility was assessed using the timed 8-foot up and go test and times to climb up and down a flight of stairs.
methodsParticipants completed the cognitive tests at baseline and the mobility measures at baseline and after 12 months of the intervention. Multiple regression analyses were conducted to determine whether baseline executive function predicted postintervention functional performance after controlling for age, sex, education, cardiorespiratory fitness, and baseline mobility levels.
resultsSelective baseline executive function measurements, particularly performance on the flanker task (β = 0.15-0.17) and the Wisconsin card sort test (β = 0.11-0.16) consistently predicted mobility outcomes at 12 months. The estimates were in the expected direction, such that better baseline performance on the executive function measures predicted better performance on the timed mobility tests independent of intervention.
conclusionExecutive functions of inhibitory control, mental set shifting, and attentional flexibility were predictive of functional mobility. Given the literature associating mobility limitations with disability, morbidity, and mortality, these results are important for understanding the antecedents to poor mobility function that well-designed interventions to improve cognitive performance can attenuate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.