ArticleJournal of the American Geriatrics Society2014
Effect of multiple pharmacy use on medication adherence and drug-drug interactions in older adults with Medicare Part D.
Article in Journal of the American Geriatrics Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Prevalence of statin-drug interactions in older people: a systematic review.European journal of clinical pharmacology · 2016Pooled it
- Mentored implementation to initiate a diabetes program in an underserved community: a pilot study.BMJ open diabetes research & care · 2021Trial
- Factors affecting cost-related medication non-adherence among US population with cardiovascular risk factors.Primary health care research & development · 2026Article
- Balancing polypharmacy and comorbidity management: cardiovascular health.Current opinion in HIV and AIDS · 2025Review
- What should patients learn? Co-designing patient education to improve medication safety, professional-patient communication, and partnership.Frontiers in medicine · 2025Article
- Assessing multilevel barriers to hydroxyurea adherence in youth with sickle cell disease using pharmacy-based refill records.Pediatric blood & cancer · 2024Article
- Medication adherence in Medicare-enrolled older adults with asthma and chronic obstructive pulmonary disease before and during COVID-19 pandemic.Therapeutic advances in chronic disease · 2023Article
- Medication delivery factors and adjuvant endocrine therapy adherence in breast cancer.Breast cancer research and treatment · 2023Article
- Clinical Pharmacy Services Enhanced by Electronic Health Record (EHR) Access: An Innovation Narrative.Pharmacy (Basel, Switzerland) · 2022Article
- Towards better reporting of the proportion of days covered method in cardiovascular medication adherence: A scoping review and new tool TEN-SPIDERS.British journal of clinical pharmacology · 2022Article
- "It's a mess sometimes": patient perspectives on provider responses to healthcare costs, and how informatics interventions can help support cost-sensitive care decisions.Journal of the American Medical Informatics Association : JAMIA · 2022Article
- Integrating Pharmacy and Registry Data Strengthens Clinical Assessments of Patient Adherence.Frontiers in pharmacology · 2022Article
- Cardiac rehabilitation for older adults: current evidence and future potential.Expert review of cardiovascular therapy · 2022Article
- Prevalence of statin utilization and adherence among privately insured subjects in the Commonwealth of Puerto Rico.Journal of managed care & specialty pharmacy · 2021Article
- The Initial Use of the Home Medication Experience Questionnaire (HOME-Q) in Community-Based Pharmacy.Journal of patient experience · 2020Article
- Patient-Oncologist Communication Regarding Oral Chemotherapy During Routine Office Visits.JCO oncology practice · 2020Article
- Self-Reported Nonadherence Associated with Pharmacy and Home Medication Management Inconvenience Factors in a US Adult Population.Patient preference and adherence · 2020Article
- The association of pharmacy fill synchronization with breast cancer endocrine therapy adherence.Cancer · 2019Article
- Adherence to treatment and related factors among patients with chronic conditions in primary care: a cross-sectional study.BMC family practice · 2019Article
- Factors Influencing Prescription Drug Synchronization: The Complex Role of Number of Medications.Journal of managed care & specialty pharmacy · 2019Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesTo assess the association between multiple pharmacy use and medication adherence and potential drug-drug interactions (DDIs) in older adults.
designCross-sectional propensity score-weighted analysis.
setting2009 claims data.
participantsA nationally representative sample of 926,956 Medicare Part D beneficiaries aged 65 and older continuously enrolled in fee-for-service Medicare and Part D that year who filled one or more prescriptions at a community retail or mail order pharmacy. MEASUREMENTS: Multiple pharmacy use was defined as concurrent (overlapping time periods) or sequential use (non-overlapping time periods) of ≥ 2 pharmacies in the year. Medication adherence was calculated using a proportion of days covered of 0.80 or greater for eight therapeutic categories (beta-blockers, renin angiotensin system antagonists, calcium channel blockers, statins, sulfonylureas, biguanides (metformin), thiazolidinediones, and dipeptidyl peptidase-IV inhibitors). Potential DDIs arising from use of certain drugs across a broad set of classes were defined as the concurrent filling of two interacting drugs.
resultsOverall, 38.1% of the sample used multiple pharmacies. Those using multiple pharmacies (concurrently or sequentially) consistently had higher adjusted odds of nonadherence (ranging from 1.10 to 1.31, P < .001) across all chronic medication classes assessed after controlling for sociodemographic, health status, and access to care factors than single pharmacy users. The adjusted predicted probability of exposure to a DDI was also slightly higher for those using multiple pharmacies concurrently (3.6%) than for single pharmacy users (3.2%, adjusted odds ratio (AOR) = 1.11, 95% confidence interval (CI) = 1.08-1.15) but lower in individuals using multiple pharmacies sequentially (2.8%, AOR = 0.85, 95% CI = 0.81-0.91).
conclusionsFilling prescriptions at multiple pharmacies was associated with lower medication adherence across multiple chronic medications and a small but statistically significant greater likelihood of DDIs in concurrent pharmacy users.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.