Evidence map›Paper›PMID 24521257›Full record

ArticleAddiction (Abingdon, England)2014

Catecholamine levels and delay discounting forecast drug use among African American youths.

Gene H Brody, Tianyi Yu, James MacKillop, Gregory E Miller, Edith Chen, Ezemenari M Obasi, Steven R H Beach

Abstract read
In one paragraph

Article in Addiction (Abingdon, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Using sign tracking to experimentally increase self-control in rats.Journal of the experimental analysis of behavior · 2024
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  7. Article
  8. Working-memory training: effects on delay discounting in male Long Evans rats.Journal of the experimental analysis of behavior · 2015
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Gene H BrodyCenter for Family Research, University of Georgia, Athens, GA, USA.
Tianyi Yu
James MacKillop
Gregory E Miller
Edith Chen
Ezemenari M Obasi
Steven R H Beach
University of Georgia · USNorthwestern University · USUniversity of Houston · US

Funding

RURAL AFRICAN AMERICAN YOUNG ADULTS' PATHWAYS TO PSYCHOSOCIAL AND PHYSICAL HEALTHR01HD030588 · NICHD · UNIVERSITY OF GEORGIA (UGA) · PI EHRLICH, KATHERINE BABCOCK · 1993 to 2023
$12.0M
Vulnerability to Drug Use & HIV: Advancing Prevention for Rural African AmericansP30DA027827 · NIDA · UNIVERSITY OF GEORGIA · PI BRODY, GENE H. · 2009 to 2018
$10.2M
Enhancing Alcoholism Pharmacotherapy Research via Behavioral EconomicsK23AA016936 · NIAAA · UNIVERSITY OF GEORGIA · PI MACKILLOP, JAMES · 2008 to 2012
$805k
CIHRNIAAA NIH HHS K23 AA016936NICHD NIH HHS R01 HD030588NIDA NIH HHS P30 DA027827NIDA NIH HHS P30DA027827
6 · The paper itself

Abstract

aimsTo test hypotheses about the contributions of the catecholamines epinephrine and norepinephrine [which serve as biological markers of life stress through sympathetic nervous system (SNS) activation], delay discounting and their interaction to the prediction of drug use among young African American adults.

designA 1-year prospective study that involved assessment of SNS activity and collection of self-report data involving delay discounting and drug use.

settingRural communities in the southeastern United States.

participantsA total of 456 African Americans who were 19 years of age at the beginning of the study. MEASUREMENTS: At age 19, participants provided overnight urine voids that were assayed for epinephrine and norepinephrine. Participants were also assessed for hyperbolic temporal discounting functions (k) and drug use. At age 20, the participants again reported their drug use.

findingsLinear regression analyses revealed that (i) catecholamine levels at age 19 forecast increases in drug use [B = 0.087, P < 0.01, 95% confidence interval (CI) = 0.025, 0.148] and (ii) among young men, catecholamine levels interacted positively with delay discounting to forecast increases in drug use (simple slope = 0.113, P < 0.001, 95% CI = 0.074, 0.152).

conclusionsHigher urinary catecholamine concentrations in their adulthood predict higher levels of drug use a year later among young African American men in the United States who engage in high, but not low, levels of delay discounting.

Indexed as

Delay DiscountingAdultBlack or African AmericanCatecholaminesEpinephrineFollow-Up StudiesHumansLongitudinal StudiesMaleNorepinephrineRural PopulationSoutheastern United StatesSubstance-Related DisordersYoung AdultCatecholaminesEpinephrineNorepinephrineAfrican Americanscatecholaminesdelay discountingdrug useepinephrinenorepinephrinerural areasstresssympathetic nervous systemyoung adults

Identifiers

PMID24521257
PMCPMC4048637
OpenAlexW2151546241

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.