Evidence map›Paper›PMID 24521254›Full record

SynthesisAmerican journal of respiratory and critical care medicine2014

Air pollution and nonmalignant respiratory mortality in 16 cohorts within the ESCAPE project.

Konstantina Dimakopoulou, Evangelia Samoli, Rob Beelen, Massimo Stafoggia, Zorana Jovanovic Andersen, Barbara Hoffmann, Paul Fischer, Mark Nieuwenhuijsen, Paolo Vineis, Wei Xun and 49 more

Abstract readMeta-Analysis
In one paragraph

Synthesis in American journal of respiratory and critical care medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Mortality and Morbidity Effects of Long-Term Exposure to Low-Level PMResearch report (Health Effects Institute) · 2021
    Pooled it
  4. Pooled it
  5. Long-term exposure to NOEnvironment international · 2020
    Pooled it
  6. Characteristics of cohort studies of long-term exposure to PMEnvironmental science and pollution research international · 2019
    Pooled it
  7. Pooled it
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Association of high PMFrontiers in public health · 2022
    Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

59 authors.

Konstantina Dimakopoulou1 Department of Hygiene, Epidemiology and Medical Statistics, Medical School, University of Athens, Athens, Greece.
Evangelia Samoli
Rob Beelen
Massimo Stafoggia
Zorana Jovanovic Andersen
Barbara Hoffmann
Paul Fischer
Mark Nieuwenhuijsen
Paolo Vineis
Wei Xun
Gerard Hoek
Ole Raaschou-Nielsen
Anna Oudin
Bertil Forsberg
Lars Modig
Pekka Jousilahti
Timo Lanki
Anu Turunen
Bente Oftedal
Per Nafstad
Per E Schwarze
Johanna Penell
Laura Fratiglioni
Niklas Andersson
Nancy Pedersen
Michal Korek
Ulf De Faire
Kirsten Thorup Eriksen
Anne Tjønneland
Thomas Becker
Meng Wang
Bas Bueno-de-Mesquita
Ming-Yi Tsai
Marloes Eeftens
Petra H Peeters
Kees Meliefste
Alessandro Marcon
Ursula Krämer
Thomas A J Kuhlbusch
Mohammad Vossoughi
Timothy Key
Kees de Hoogh
Regina Hampel
Annette Peters
Joachim Heinrich
Gudrun Weinmayr
Hans Concin
Gabriele Nagel
Alex Ineichen
Bénédicte Jacquemin
Morgane Stempfelet
Alice Vilier
Fulvio Ricceri
Carlotta Sacerdote
Xanthi Pedeli
Michalis Katsoulis
Antonia Trichopoulou
Bert Brunekreef
Klea Katsouyanni

Funding

Interstitial Cystitis in Swedish TwinsU01DK066134 · NIDDK · KAROLINSKA INSTITUTE · PI PEDERSEN, NANCY L · 2004 to 2008
$2.9M
DEMENTIA IN TWINSR01AG008724 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GATZ, MARGARET · 1990 to 2002
$1.4M
Medical Research Council G0801056NIA NIH HHS AG-08724NIA NIH HHS R01 AG008724NIDDK NIH HHS DK U01-066134
6 · The paper itself

Abstract

rationaleProspective cohort studies have shown that chronic exposure to particulate matter and traffic-related air pollution is associated with reduced survival. However, the effects on nonmalignant respiratory mortality are less studied, and the data reported are less consistent.

objectivesWe have investigated the relationship of long-term exposure to air pollution and nonmalignant respiratory mortality in 16 cohorts with individual level data within the multicenter European Study of Cohorts for Air Pollution Effects (ESCAPE).

methodsData from 16 ongoing cohort studies from Europe were used. The total number of subjects was 307,553. There were 1,559 respiratory deaths during follow-up. MEASUREMENTS AND MAIN

resultsAir pollution exposure was estimated by land use regression models at the baseline residential addresses of study participants and traffic-proximity variables were derived from geographical databases following a standardized procedure within the ESCAPE study. Cohort-specific hazard ratios obtained by Cox proportional hazard models from standardized individual cohort analyses were combined using metaanalyses. We found no significant associations between air pollution exposure and nonmalignant respiratory mortality. Most hazard ratios were slightly below unity, with the exception of the traffic-proximity indicators.

conclusionsIn this study of 16 cohorts, there was no association between air pollution exposure and nonmalignant respiratory mortality.

Indexed as

AdultAgedAged, 80 and overAir PollutantsAir PollutionCohort StudiesEnvironmental ExposureEuropeFemaleFollow-Up StudiesHumansMaleMiddle AgedParticulate MatterProportional Hazards ModelsRegression AnalysisAir PollutantsParticulate Matter

Identifiers

PMID24521254
PMCPMC5447285

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.