ArticleWorld journal of surgical oncology2014
Preoperative thrombocytosis is a significant unfavorable prognostic factor for patients with resectable non-small cell lung cancer.
Article in World journal of surgical oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic value of pretreatment platelet counts in lung cancer: a systematic review and meta-analysis.BMC pulmonary medicine · 2020Pooled it
- Trial
- Preoperative platelet count as an independent predictor of long-term outcomes among patients undergoing resection for intrahepatic cholangiocarcinoma.Journal of surgical oncology · 2024Article
- Tumor-infiltrating platelets promote the growth of lung adenocarcinoma.Translational oncology · 2024Article
- Development and validation of a [European radiology · 2023Article
- The prognostic role of pre-cystectomy thrombocytosis in invasive bladder cancer.International urology and nephrology · 2022Article
- Platelet Count and Survival after Cancer.Cancers · 2022Article
- Prognostic Impact of the Advanced Lung Cancer Inflammation Index (ALI) in Metastatic Non-Small Cell Lung Cancer Treated with First Line Chemotherapy.Asian Pacific journal of cancer prevention : APJCP · 2021Article
- The association between thrombocytosis and subtype of lung cancer: a systematic review and meta-analysis.Translational cancer research · 2021Article
- Platelets, Thrombocytosis, and Ovarian Cancer Prognosis: Surveying the Landscape of the Literature.International journal of molecular sciences · 2020Review
- Preoperative plateletcrit is a Prognostic Biomarker for Survival in Patients with Non-Small Cell Lung Cancer.Journal of Cancer · 2020Article
- Pre-treatment systemic immune-inflammation represents a prognostic factor in patients with advanced non-small cell lung cancer.Annals of translational medicine · 2019Article
- Comparison of Hematologic and Other Prognostic Markers in Metastatic Colorectal Cancer.Journal of gastrointestinal cancer · 2019Article
- Prognostic role of preoperative platelet, fibrinogen, and D-dimer levels in patients with non-small cell lung cancer: A multicenter prospective study.Thoracic cancer · 2019Article
- The clinicopathological and prognostic role of thrombocytosis in patients with cancer: A meta-analysis.Oncology letters · 2017Article
- Prognostic value of combination of preoperative platelet count and mean platelet volume in patients with resectable non-small cell lung cancer.Oncotarget · 2017Article
- Article
- Cancer and Thrombosis: The Platelet Perspective.Frontiers in cell and developmental biology · 2016Review
- Resistance to multikinase inhibitor actions mediated by insulin like growth factor-1.Journal of experimental & clinical cancer research : CR · 2015Article
- Prognostic role of elevated platelet count in patients with lung cancer: a systematic review and meta-analysis.International journal of clinical and experimental medicine · 2015Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies have reported that pretreatment thrombocytosis is associated with poor outcomes in several cancer types. This study was designed to evaluate the prognostic significance of preoperative thrombocytosis in patients with non-small cell lung cancer (NSCLC) who undergo surgery.
methodsWe retrospectively reviewed the records of 199 patients who underwent R0 resection for NSCLC between May 2003 and July 2006 at Seoul National University Bundang Hospital, Seongnam, Korea.
resultsThe frequency of preoperative thrombocytosis was 7.5% (15/199). Patients with preoperative thrombocytosis had shorter overall survival (OS, P = 0.003) and disease-free survival (DFS, P = 0.005) than those without thrombocytosis. In multivariable analysis, patients with preoperative thrombocytosis had a significantly greater risk of death and recurrence than those without preoperative thrombocytosis (risk of death: hazard ratio (HR) 2.98, 95% confidence interval (CI) 1.39 to 6.37, P = 0.005; risk of recurrence: HR 2.47, 95% CI 1.22 to 5.01, P = 0.012). A tendency towards a shorter OS and DFS was observed in three patients with persistent thrombocytosis during the follow-up period when compared with those of patients who recovered from thrombocytosis after surgery.
conclusionsPreoperative thrombocytosis was valuable for predicting the prognosis of patients with NSCLC. Special attention should be paid to patients with preoperative and postoperative thrombocytosis.
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