ArticleBMC infectious diseases2014
Molecular epidemiology of giardiasis among Orang Asli in Malaysia: application of the triosephosphate isomerase gene.
Article in BMC infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence and risk factors of intestinal protozoal infections among patients in Malaysia: A systematic review and meta-analysis.PloS one · 2025Pooled it
- Exposure to Animal Feces and Human Health: A Systematic Review and Proposed Research Priorities.Environmental science & technology · 2017Pooled it
- First Assessment of Risk Factors forMicroorganisms · 2025Article
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- Assessing seroprevalence and associated risk factors for multiple infectious diseases in Sabah, Malaysia using serological multiplex bead assays.Frontiers in public health · 2022Article
- Zoonotic giardiasis: an update.Parasitology research · 2021Review
- Current state of infection and prevalence of giardiasis in Malaysia: a review of 20 years of research.PeerJ · 2021Article
- The controversies surroundingCurrent research in parasitology & vector-borne diseases · 2021Review
- Prevalence and genetic characterization ofParasite epidemiology and control · 2020Article
- Comparative Transcriptome Analysis ofFrontiers in immunology · 2020Article
- Genetic analysis of Giardia duodenalis isolates from children of low-income families living in an economically successful region in Southeastern Brazil.Revista do Instituto de Medicina Tropical de Sao Paulo · 2020Article
- Genotyping of Giardia duodenalis in children in upper Egypt using assemblage- specific PCR technique.PloS one · 2020Article
- Pathogens transmitted in animal feces in low- and middle-income countries.International journal of hygiene and environmental health · 2018Review
- Molecular epidemiology of Giardia duodenalis infection in humans in Southern Ethiopia: a triosephosphate isomerase gene-targeted analysis.Infectious diseases of poverty · 2018Article
- Multilocus sequence analysis of Giardia spp. isolated from patients with diarrhea in Austria.Parasitology research · 2017Article
- Review
- Different risk factors for infection with Giardia lamblia assemblages A and B in children attending day-care centres.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2016Article
- Determining intestinal parasitic infections (IPIs) in inmates from Kajang Prison, Selangor, Malaysia for improved prison management.BMC infectious diseases · 2015Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundGiardia duodenalis is a flagellate parasite which has been considered the most common protozoa infecting human worldwide. Molecular characterization of G. duodenalis isolates have revealed the existence of eight groups (Assemblage A to H) which differ in their host distribution. Assemblages A and B are found in humans and in many other mammals.
methodsThis cross-sectional study was conducted to identify assemblage's related risk factors of G. duodenalis among Orang Asli in Malaysia. Stool samples were collected from 611 individuals aged between 2 and 74 years old of whom 266 were males and 345 were females. Socioeconomic data were collected through a pre-tested questionnaire. All stool samples were processed with formalin-ether sedimentation and Wheatley's trichrome staining techniques for the primary identification of G. duodenalis. Molecular identification was carried out by the amplification of a triosephosphate isomerase gene using nested-PCR assay.
resultsSixty-two samples (10.2%) were identified as assemblage A and 36 (5.9%) were assemblage B. Risk analysis based on the detected assemblages using univariate and logistic regression analyses identified subjects who have close contact with household pets i.e. dogs and cats (OR = 2.60; 95% CI = 1.42, 4.78; P = 0.002) was found to be significant predictor for assemblage A. On the other hand, there were three significant risk factors caused by assemblage B: (i) children ≤15 years old (OR = 2.33; 95% CI = 1.11, 4.87; P = 0.025), (ii) consuming raw vegetables (OR = 2.82; 95% CI = 1.27, 6.26; P = 0.011) and (iii) the presence of other family members infected with giardiasis (OR = 6.31; 95% CI = 2.99, 13.31; P < 0.001).
conclusionsThe present study highlighted that G. duodenalis infection among Orang Asli was caused by both assemblages with significant high prevalence of assemblage A. Therefore, taking precaution after having contact with household pets and their stool, screening and treating infected individuals, awareness on the importance of good health practices and washing vegetables are the practical intervention ways in preventing giardiasis in Orang Asli community.
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