ArticlePlant physiology2014
A subfamily of putative cytokinin receptors is revealed by an analysis of the evolution of the two-component signaling system of plants.
Article in Plant physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22 citing papers in PubMed, 41 citations in OpenAlex.
- The origin and early evolution of cytokinin signaling.Frontiers in plant science · 2023Review
- Article
- Cytokinin Perception in Ancient Plants beyond Angiospermae.International journal of molecular sciences · 2021Article
- Evolution of the Cytokinin Dehydrogenase (CKX) Domain.Journal of molecular evolution · 2021Article
- Phytohormone biosynthesis and signaling pathways of mosses.Plant molecular biology · 2021Review
- Isopentenyltransferases as master regulators of crop performance: their function, manipulation, and genetic potential for stress adaptation and yield improvement.Plant biotechnology journal · 2021Review
- Characterization of CHARK, an unusual cytokinin receptor of rice.Scientific reports · 2021Article
- The Journey from Two-Step to Multi-Step Phosphorelay Signaling Systems.Current genomics · 2021Review
- The Synthesis of ³H-Labelled 8-Azido-N⁶-Benzyladenine and Related Compounds for Photoaffinity Labelling of Cytokinin-Binding Proteins.Molecules (Basel, Switzerland) · 2019Article
- Diversity and Evolution of Sensor Histidine Kinases in Eukaryotes.Genome biology and evolution · 2019Article
- Article
- What do archaeal and eukaryotic histidine kinases sense?F1000Research · 2019Review
- Light-regulated PAS-containing histidine kinases delay gametophore formation in the moss Physcomitrella patens.Journal of experimental botany · 2018Article
- The effects of repeated whole genome duplication events on the evolution of cytokinin signaling pathway.BMC evolutionary biology · 2018Article
- Article
- Arabidopsis response regulator 22 inhibits cytokinin-regulated gene transcription in vivo.Protoplasma · 2017Article
- CHASE domain-containing receptors play an essential role in the cytokinin response of the moss Physcomitrella patens.Journal of experimental botany · 2016Article
- Survey of Genes Involved in Biosynthesis, Transport, and Signaling of Phytohormones with Focus onBioinformatics and biology insights · 2016Article
- The role of cis-zeatin-type cytokinins in plant growth regulation and mediating responses to environmental interactions.Journal of experimental botany · 2015Review
- Insights into the origin and evolution of the plant hormone signaling machinery.Plant physiology · 2015Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The two-component signaling system--the major signaling pathway of bacteria--is found among higher eukaryotes only in plants, where it regulates diverse processes, such as the signaling of the phytohormone cytokinin. Cytokinin is perceived by a hybrid histidine (His) kinase receptor, and the signal is transduced by a multistep phosphorelay system of His phosphotransfer proteins and different classes of response regulators (RRs). To shed light on the origin and evolution of the two-component signaling system members in plants, we conducted a comprehensive domain-based phylogenetic study across the relevant kingdoms, including Charophyceae algae, the group of green algae giving rise to land plants. Surprisingly, we identified a subfamily of cytokinin receptors with members only from the early diverging land plants Marchantia polymorpha and Physcomitrella patens and then experimentally characterized two members of this subfamily. His phosphotransfer proteins of Charophyceae seemed to be more closely related to land plants than to other groups of green algae. Farther down the signaling pathway, the type-B RRs were found across all plant clades, but many members lack either the canonical Asp residue or the DNA binding domain. In contrast, the type-A RRs seemed to be limited to land plants. Finally, the analysis provided hints that one additional group of RRs, the type-C RRs, might be degenerated receptors and thus, of a different evolutionary origin than bona fide RRs.
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