ArticleObesity (Silver Spring, Md.)2014
BMI and the risk of colorectal adenoma in African-Americans.
Article in Obesity (Silver Spring, Md.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 35 citations in OpenAlex.
- Development of an Interpretable Triage Tool for Colorectal Polyp Risk Stratification Within a Population-Based Screening Program: Machine Learning Approach.JMIR medical informatics · 2026Article
- Colorectal Cancer Risk and Protective Factors Among People of African Descent: A Systematic Review and Meta-Analysis.Cureus · 2025Review
- Correlation Between Skeletal Muscle Mass and Different Pathological Types of Colorectal Polyp in Chinese Asymptomatic Population.International journal of general medicine · 2025Article
- Trends and Symptoms Among Increasing Proportion of African Americans with Early-Onset Colorectal Cancer over a 60-Year Period.Digestive diseases and sciences · 2025Article
- Expression of cyclooxygenase-2 (COX-2) in colorectal adenoma in an indigenous African population in northern Nigeria.African journal of laboratory medicine · 2025Article
- The Innate Immune System Surveillance Biomarker p87 in African Americans and Caucasians with Small High-Grade Dysplastic Adenoma [SHiGDA] and Right-SidedGastrointestinal disorders (Basel, Switzerland) · 2024Article
- MAFLD with central obesity is associated with increased risk of colorectal adenoma and high-risk adenoma.BMC gastroenterology · 2024Article
- Metabolic risk factors link unhealthy lifestyles to the risk of colorectal polyps in China.Preventive medicine reports · 2023Article
- Validity of pathological diagnosis for early colorectal cancer in genetic background.Cancer medicine · 2023Article
- Visceral Obesity Is a More Important Factor for Colorectal Adenomas than Skeletal Muscle or Body Fat.Cancers · 2022Article
- Genetic Signatures of Glucose Homeostasis: Synergistic Interplay With Long-Term Exposure to Cigarette Smoking in Development of Primary Colorectal Cancer Among African American Women.Clinical and translational gastroenterology · 2021Article
- Self-reported Metabolic Risk Factor Associations with Adenomatous, Sessile Serrated, and Synchronous Adenomatous and Sessile Serrated Polyps.Cancer prevention research (Philadelphia, Pa.) · 2021Observational
- Prognostic Value of Preoperative Fibrinogen for Predicting Clinical Outcome in Patients with Nonmetastatic Colorectal Cancer.Cancer management and research · 2020Article
- Efficacy, safety, and tolerability of a ready-to-drink bowel preparation in overweight and obese adults: subanalysis by body mass index from a phase III, assessor-blinded study.Therapeutic advances in gastroenterology · 2020Article
- Obesity, diabetes and the risk of colorectal adenoma and cancer.BMC endocrine disorders · 2019Article
- Increased Frequency of KRAS Mutations in African Americans Compared with Caucasians in Sporadic Colorectal Cancer.Clinical and translational gastroenterology · 2017Article
- How significant is the association between metabolic syndrome and prevalence of colorectal neoplasia?World journal of gastroenterology · 2016Review
- Increased MACC1 levels in tissues and blood identify colon adenoma patients at high risk.Journal of translational medicine · 2016Article
- Obesity and colorectal cancer: molecular features of adipose tissue.Journal of translational medicine · 2016Review
- Genetic Basis for Colorectal Cancer Disparities.Current colorectal cancer reports · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 1 institution in 1 country.
Funding
Abstract
objectivesObesity is associated with the activation of the molecular pathways that increase the risk of colorectal cancer. Increasing body mass index may accelerate the development of adenomatous polyps, the antecedent lesion of colorectal cancer. The aim of this study was to assess the BMI effect on the risk of colonic polyp and adenoma in African-American.
methodsThe records of 923 patients who underwent colonoscopy were examined. Demographic and clinical data were collected before colonoscopy. Polyp and adenoma diagnosis were confirmed by pathology examinations.
resultsOverall, 43% of the patients were male, median age was 57 years and 77% had BMI ≥ 25.0 kg/m(2) . The frequency of colorectal polyps and adenomas were 61 and 35%, respectively. BMI ≥ 25.0 (OR = 1.61, 95% CI = 1.14-2.26), smoking (OR = 1.61, 95% CI = 1.15-2.26) and history of colon polyps (OR = 1.64, 95% CI = 1.09-2.47) were associated with higher risk of colon polyp. BMI ≥ 25.0 (OR = 1.81, 95% CI = 1.24-2.62), age (OR = 1.04, 95% CI = 1.02-2.05 for each year), male gender (OR = 1.38, 95% CI = 1.02-1.86), and smoking (OR = 1.73, 95% CI = 1.23-2.42) were associated with higher risk of colon adenoma.
conclusionMale and overweight African-Americans are at higher risk of colorectal adenoma. The findings of this study could be applied for risk stratification and modifying the colorectal cancer prevention including screening guideline in African Americans.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.