SynthesisSleep & breathing = Schlaf & Atmung2014
A systematic review and quantitative assessment of sleep-disordered breathing during pregnancy and perinatal outcomes.
Synthesis in Sleep & breathing = Schlaf & Atmung, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02755831 (Randomized Controlled Trial for a Sleep Study and Targeted CPAP Therapy for Obstructive Sleep Apnea to Reduce the Incidence Adverse Pregnancy Related Outcomes), which is not on this map. Cited by 47 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Controlled Trial for a Sleep Study and Targeted CPAP Therapy for Obstructive Sleep Apnea to Reduce the Incidence Adverse Pregnancy Related Outcomes
Who cites it
47 citing papers in PubMed, 5 syntheses or guidelines pooled it, 112 citations in OpenAlex.
- Fetal and neonatal outcomes of pregnancies complicated by maternal sleep-disordered breathing: a systematic review.Frontiers in physiology · 2026Pooled it
- Effect of the maternal sleep disturbances and obstructive sleep apnea on feto-placental Doppler: A systematic review.Journal of sleep research · 2025Pooled it
- Associations of plasma hypocretin-1 with metabolic and reproductive health: Two systematic reviews of clinical studies.Sleep medicine reviews · 2020Pooled it
- The prevalence of obstructive sleep apnea and its association with pregnancy-related health outcomes: a systematic review and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2019Pooled it
- Society of Anesthesia and Sleep Medicine Guidelines on Preoperative Screening and Assessment of Adult Patients With Obstructive Sleep Apnea.Anesthesia and analgesia · 2016Guideline
- Sleep quality and health among pregnant smokers.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Trial
- Trial
- Trial
- Modifying maternal sleep position in the third trimester of pregnancy with positional therapy: a randomised pilot trial.BMJ open · 2018Trial
- Association between obstructive sleep apnea and perinatal outcomes in a cohort of Japanese pregnant women: a prospective observational study.Sleep & breathing = Schlaf & Atmung · 2026Observational
- Continuous positive airway pressure versus usual care for obstructive sleep apnoea in pregnancy: a two-step pilot trial.Pilot and feasibility studies · 2025Article
- The effect of maternal sleep quality in late pregnancy on prenatal, birth and early postnatal outcomes.Journal of sleep research · 2024Article
- Association Between Sleep Quality and Duration During Pregnancy and Risk of Infant Being Small for Gestational Age: Prospective Birth Cohort Study.Healthcare (Basel, Switzerland) · 2024Article
- Obstructive Sleep Apnea in Pregnancy: A Comprehensive Review of Maternal and Fetal Implications.Neurology international · 2024Review
- Gestational Intermittent Hypoxia Impairs ATJournal of biotechnology and biomedicine · 2024Article
- Vision-based detection and quantification of maternal sleeping position in the third trimester of pregnancy in the home setting-Building the dataset and model.PLOS digital health · 2023Article
- Longitudinal Sleep Study in Pregnancy: Cohort Profile and Prevalence and Risk Factors for Sleep Symptoms in the First Trimester.International journal of environmental research and public health · 2023Article
- Common sleep disorders in pregnancy: a review.Frontiers in medicine · 2023Review
- Review
- Cardio-Obstetrics: the Next Frontier in Cardiovascular Disease Prevention.Current atherosclerosis reports · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePrevious investigations have suggested a strong association between sleep-disordered breathing (SDB) during pregnancy and perinatal outcomes. However, the results of the following replication studies were not always concordant. Therefore, this meta-analysis was conducted to evaluate the more reliable estimate.
methodsA systematic literature search was performed on PubMed, Springer Link, and EMBASE to identify all eligible studies published before August 2013. Summary odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using fixed or random effects model.
resultsA total of 24 publications met the inclusion criteria and were included in this meta-analysis. Findings demonstrated that moderate-to-severe SDB during pregnancy was associated with gestational diabetes mellitus (OR=1.78; 95% CI, 1.29 to 2.46), pregnancy-related hypertension (OR=2.38; 95% CI, 1.63 to 3.47), preeclampsia (OR=2.19; 95% CI, 1.71 to 2.80), preterm delivery (OR=1.98; 95% CI, 1.59 to 2.48), low birth weight (OR=1.75; 95% CI, 1.33 to 2.32), neonatal intensive care unit (NICU) admission (OR=2.43; 95% CI, 1.61 to 3.68), intrauterine growth restriction (OR=1.44; 95% CI, 1.22 to 1.71), and Apgar score of <7 at 1 min (OR=1.78; 95% CI, 1.10 to 2.91) based on all studies but not gestational age and birth weight.
conclusionsThis meta-analysis revealed that moderate-to-severe SDB during pregnancy may be associated with most of adverse perinatal outcomes. Further well-designed studies are warranted to confirm our findings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.