ArticleClinics (Sao Paulo, Brazil)2014
Can Doppler or contrast-enhanced ultrasound analysis add diagnostically important information about the nature of breast lesions?
Article in Clinics (Sao Paulo, Brazil), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review and meta-analysis comparing the diagnostic capability of automated breast ultrasound and contrast-enhanced ultrasound in breast cancer.Frontiers in oncology · 2023Pooled it
- Diagnostic utility of ultrasonography in the management of postoperative fluid collections and abdominal indwelling catheters following pancreaticoduodenectomy: retrospective cohort study.European journal of medical research · 2025Article
- Evaluation of diagnostic value of Doppler ultrasound in the diagnosis of malignant breast masses.European journal of translational myology · 2024Article
- Superb microvascular imaging for evaluation of microvascularity in breast nodules compared with conventional Doppler imaging.Quantitative imaging in medicine and surgery · 2023Article
- The Importance of Superb Microvascular Imaging for the Differentiation of Malignant Breast Lesions from Benign Lesions.European journal of breast health · 2022Article
- Superb Microvascular Imaging Technology Can Improve the Diagnostic Efficiency of the BI-RADS System.Frontiers in oncology · 2021Article
- Microvascular Ultrasonic Imaging of Angiogenesis Identifies Tumors in a Murine Spontaneous Breast Cancer Model.International journal of biomedical imaging · 2020Article
- Targeted Fe-doped silica nanoparticles as a novel ultrasound-magnetic resonance dual-mode imaging contrast agent for HER2-positive breast cancer.International journal of nanomedicine · 2019Article
- A Simple Ultrasound Based Classification Algorithm Allows Differentiation of Benign from Malignant Breast Lesions by Using Only Quantitative Parameters.Molecular imaging and biology · 2018Article
- Diagnostic evaluations of ultrasound and magnetic resonance imaging in mammary duct ectasia and breast cancer.Oncology letters · 2018Article
- Imaging Considerations and Interprofessional Opportunities in the Care of Breast Cancer Patients in the Neoadjuvant Setting.Seminars in oncology nursing · 2017Review
- Sonographic features of invasive ductal breast carcinomas predictive of malignancy grade.The Indian journal of radiology & imagingArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesDespite evidence suggesting that Doppler ultrasonography can help to differentiate between benign and malignant breast lesions, it is rarely applied in clinical practice. The aim of this study was to determine whether certain vascular features of breast masses observed by duplex Doppler and color Doppler ultrasonography (before and/or after microbubble contrast injection) add information to the gray-scale analysis and support the Breast Imaging-Reporting and Data System (BI-RADS) classification.
methodsSeventy solid lesions were prospectively evaluated with gray-scale ultrasonography, color Doppler ultrasonography, and contrast-enhanced ultrasonography. The morphological analysis and lesion vascularity were correlated with the histological results.
resultsPercutaneous core biopsies revealed that 25/70 (17.5%) lesions were malignant, while 45 were benign. Hypervascular lesions with tortuous and central vessels, a resistive index (RI)≥ 0.73 before contrast injection, and an RI≥ 0.75 after contrast injection were significantly predictive of malignancy (p<0.001).
conclusionThe combination of gray-scale ultrasonography data with unenhanced or enhanced duplex Doppler and color Doppler US data can provide diagnostically useful information. These techniques can be easily implemented because Doppler devices are already present in most health centers.
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