Evidence map›Paper›PMID 24518554›Full record

ArticleHuman vaccines & immunotherapeutics2014

Reply to Shin and Bayry on "An age-related decline of CD62L and vaccine response: a role of microRNA 92a?".

Thomas Vorup-Jensen, Carina Rosenberg, Eskild Petersen

Abstract readLetterComment
In one paragraph

Article in Human vaccines & immunotherapeutics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Thomas Vorup-JensenDepartment of Biomedicine; Aarhus University; Aarhus, Denmark.
Carina RosenbergDepartment of Biomedicine; Aarhus University; Aarhus, Denmark.
Eskild PetersenDepartment of Clinical Medicine; Aarhus University; Aarhus, Denmark; Department of Infectious Diseases; Aarhus University Hospital-Skejby; Aarhus, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging of the human body affects the immune system by a decline in the ability to raise a response to challenges such as microbial infections or vaccinations. In the very elderly, the decline in such functions appears to relate to a reduced expression of certain co-stimulatory molecules expressed by T lymphocytes. More recently, attention has been drawn to the adhesion molecule CD62L, where differences in expression and function of this molecule between younger and older individuals are suspected to be a part of immunosenescence in the elderly.

Indexed as

AgingCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesFemaleHepatitis B AntibodiesHepatitis B Surface AntigensHumansL-SelectinMaleHepatitis B AntibodiesHepatitis B Surface AntigensL-Selectinadhesion moleculeageCD62LglycosylationHBV

Identifiers

PMID24518554
PMCPMC4896509

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.