Evidence map›Paper›PMID 24517180›Full record

Observational studyBJOG : an international journal of obstetrics and gynaecology2014

Reporting errors, incidence and risk factors for postpartum haemorrhage and progression to severe PPH: a prospective observational study.

A Briley, P T Seed, G Tydeman, H Ballard, M Waterstone, J Sandall, L Poston, R M Tribe, S Bewley

Abstract readObservational Study
In one paragraph

Observational study in BJOG : an international journal of obstetrics and gynaecology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

A BrileyDivision of Women's Health, Women's Health Academic Centre, King's College London and King's Health Partners, St Thomas' Hospital Campus, London, UK.
P T Seed
G Tydeman
H Ballard
M Waterstone
J Sandall
L Poston
R M Tribe
S Bewley

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo quantify reporting errors, measure incidence of postpartum haemorrhage (PPH) and define risk factors for PPH (≥500 ml) and progression to severe PPH (≥1500 ml).

designProspective observational study.

settingTwo UK maternity services. POPULATION: Women giving birth between 1 August 2008 and 31 July 2009 (n = 10 213).

methodsWeighted sampling with sequential adjustment by multivariate analysis.

main outcome measuresIncidence and risk factors for PPH and progression to severe PPH.

resultsErrors in transcribing blood volume were frequent (14%) with evidence of threshold preference and avoidance. The incidences of PPH ≥500, ≥1500 and ≥2500 ml were 33.7% (95% CI 31.2-36.2), 3.9% (95% CI 3.3-4.6) and 0.8% (95% CI 0.6-1.0). New independent risk factors predicting PPH ≥ 500 ml included Black African ethnicity (adjusted odds ratio [aOR] 1.77, 95% CI 1.31-2.39) and assisted conception (aOR 2.93, 95% CI 1.30-6.59). Modelling demonstrated how prepregnancy- and pregnancy-acquired factors may be mediated through intrapartum events, including caesarean section, elective (aOR 24.4, 95% CI 5.53-108.00) or emergency (aOR 40.5, 95% CI 16.30-101.00), and retained placenta (aOR 21.3, 95% CI 8.31-54.7). New risk factors were identified for progression to severe PPH, including index of multiple deprivation (education, skills and training) (aOR 1.75, 95% CI 1.11-2.74), multiparity without caesarean section (aOR 1.65, 95% CI 1.20-2.28) and administration of steroids for fetal reasons (aOR 2.00, 95% CI 1.24-3.22).

conclusionsSequential, interacting, traditional and new risk factors explain the highest rates of PPH and severe PPH reported to date.

Indexed as

Disease ProgressionFemaleHumansIncidenceMedical ErrorsPostpartum HemorrhagePregnancyProspective StudiesRisk FactorsRisk ManagementSeverity of Illness IndexBlood lossobservational studypregnancyprogressionrisk factorssevere adverse maternal morbidity

Identifiers

PMID24517180
PMCPMC4282054

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.