Evidence map›Paper›PMID 24516779›Full record

ArticleACS macro letters2013

Water-soluble Semiconducting Nanoparticles for Imaging.

Chinessa T Adkins, Julia N Dobish, Scott Brown, Eva Harth

Abstract read
In one paragraph

Article in ACS macro letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Advances in Fluorescent Single-Chain Nanoparticles.Molecules (Basel, Switzerland) · 2017
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chinessa T AdkinsDepartment of Chemistry, Vanderbilt University, 7619 Stevenson Center, Nashville, Tennessee, USA.
Julia N DobishDepartment of Chemistry, Vanderbilt University, 7619 Stevenson Center, Nashville, Tennessee, USA.
Scott BrownDepartment of Chemistry, Vanderbilt University, 7619 Stevenson Center, Nashville, Tennessee, USA.
Eva HarthDepartment of Chemistry, Vanderbilt University, 7619 Stevenson Center, Nashville, Tennessee, USA.

Funding

Chemistry-Biology Interface Training GrantT32GM065086 · NIGMS · VANDERBILT UNIVERSITY · PI BACHMANN, BRIAN O, SULIKOWSKI, GARY ALLEN · 2002 to 2022
$7.0M
Multifunctional well-defined polyester particles in any nanoscopic sizeR21EB009223 · NIBIB · VANDERBILT UNIVERSITY · PI HARTH, EVA · 2010 to 2011
$412k
NIBIB NIH HHS R21 EB009223NIGMS NIH HHS T32 GM065086
6 · The paper itself

Abstract

Water-soluble semiconducting nanoparticles are prepared from individually collapsed and crosslinked ABA triblock copolymers and are further modified to carry imaging units and allyl functionalities for postmodification. Ethylene oxide modified polyfluorene forms the center block (B) and is transformed into a telechelic macroinitator. In a nitroxide mediated living free radical polymerization, polyacrylate blocks (A) are grown to give the ABA triblock copolymer. Low-temperature benzocyclobutene crosslinking groups are attached to collapse and site-isolate the center block (A). The nanoparticles were further modified by pegylation to enhance the solubility and by catechol groups to provide complexing sites for magnetic resonance imaging (MRI) reagents such as gadolinium. The reported materials are water-soluble and encompassing fluorescence and MRI to become biocompatible "organic quantum dots" with the possibility to interact actively with biological entities.

Indexed as

biosensingintermolecular chain collapseMRI imagingsite isolation of fluorophoresWater soluble organic quantum dots

Identifiers

PMID24516779
PMCPMC3917510

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.