ArticlePLoS neglected tropical diseases2014
Anti-Anisakis IgE seroprevalence in the healthy Croatian coastal population and associated risk factors.
Article in PLoS neglected tropical diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- World-wide prevalence of Anisakis larvae in fish and its relationship to human allergic anisakiasis: a systematic review.Parasitology research · 2020Pooled it
- Anisakis sensitization in different population groups and public health impact: A systematic review.PloS one · 2018Pooled it
- Seroprevalence of IgG and IgE Antibodies AgainstAntibodies (Basel, Switzerland) · 2025Article
- Anisakidae and Anisakidosis: A Public Health Perspective.Pathogens (Basel, Switzerland) · 2025Review
- Screening of Anisakis-Related Allergies and Associated Factors in a Mediterranean Community Characterized by High Seafood Consumption.Foods (Basel, Switzerland) · 2024Article
- Zoonotic Marine Nematode Infection of Fish Products in Landlocked Country, Slovakia.Emerging infectious diseases · 2023Article
- Basophil Activation Test in the Diagnosis ofPathogens (Basel, Switzerland) · 2023Article
- Lack of iron, zinc, and vitamins as a contributor to the etiology of atopic diseases.Frontiers in nutrition · 2022Review
- Analysis of Ani s 7 and Ani s 1 allergens as biomarkers of sensitization and allergy severity in human anisakiasis.Scientific reports · 2020Article
- Urticaria and silent parasitism by Ascaridoidea: Component-resolved diagnosis reinforces the significance of this association.PLoS neglected tropical diseases · 2020Article
- Anisakis Sensitization in the Croatian fish processing workers: Behavioral instead of occupational risk factors?PLoS neglected tropical diseases · 2020Article
- Excretory/secretory products of anisakid nematodes: biological and pathological roles.Acta veterinaria Scandinavica · 2017Review
- New Perspectives on the Diagnosis of Allergy to Anisakis spp.Current allergy and asthma reports · 2017Review
- A case report of Anisakis pegreffii (Nematoda, Anisakidae) identified from archival paraffin sections of a Croatian patient.BMC infectious diseases · 2016Article
- Activity of tea tree (Melaleuca alternifolia) essential oil against L3 larvae of Anisakis simplex.BioMed research international · 2014Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe main objective of the study was to determine the degree of sensitization to Anisakis spp. antigens in healthy coastal population of Dalmatia given the high thermally unprocessed fish intake rate present in this area, suggested as a significant risk factor for anisakiasis. We performed a monocenter, cross-sectional pilot study stratified by geographic area of residence, conducted at the County secondary healthcare provider Medicine-biochemical Laboratory in Split (Croatia), from November 2010 till December 2011, on 500 unpaid volunteer subjects undergoing routine blood analysis and belonging to the south coast of the Adriatic Sea. METHODOLOGY/PRINCIPAL
findingsWe studied the IgE seroprevalence to Anisakis spp. Ani s l and Ani s 7 allergens by indirect ELISA in healthy subjects, which were selected at random in the region of Dalmatia (Southern Croatia), among islands, coastal urban and inland rural populations. In order to detect possible cross-reactivity to other human helminthes, serum samples were tested also for the presence of IgG antibodies to Ascaris lumbricoides and Toxocara canis. The overall and coastal Anisakis seroprevalences for the sampled population were 2% and 2.5%, respectively. The logistic univariate regression analysis confirmed that regarding anti-Anisakis IgE seroprevalence, raw fish intake, daily fish intake, homemade origin of fish dish and occupational contact (professional, artisanal or hobby contact with fishery or fish industry) were risk factors associated to Anisakis spp. sensitization, but neither of the variables was exclusive for a particular seropositive population. Also, a significant difference was observed between seropositive and seronegative subjects that had stated allergy or symptoms associated with allergy (atopic dermatitis, asthma or rhinitis) in their previous history. CONCLUSIONS/SIGNIFICANCE: Being the first in Croatia, our study underlines the necessity of incorporating Anisakis spp. allergens in routine hypersensitivity testing of coastal population.
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