ArticlePloS one2014
Maternal factors associated with fetal growth and birthweight are independent determinants of placental weight and exhibit differential effects by fetal sex.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
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Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of maternal anemia on low-birth-weight in Sub-Sahara African countries: Systematic review and meta-analysis.PloS one · 2025Pooled it
- Effect of Mediterranean diet or mindfulness-based stress reduction during pregnancy on placental volume and perfusion: A subanalysis of the IMPACT BCN randomized clinical trial.Acta obstetricia et gynecologica Scandinavica · 2024Trial
- Heat stress, divergent nutrition level, and late pregnancy in hair sheep: effects upon cotyledon development and litter weight at birth.Tropical animal health and production · 2015Trial
- Placental Gene Expression in Women with Excessive Gestational Weight Gain.International journal of molecular sciences · 2026Article
- Exploring the interplay of maternal anemia and BMI in determining low birth weight among rural Indian children: evidence from NFHS-5.Journal of health, population, and nutrition · 2026Article
- Longitudinal Changes in General Overweight and Obesity, and Central Obesity from Birth to Early Adolescence.Nutrients · 2026Article
- Mind the Litter: The Critical Role of Intralitter Variables in Reproductive and Developmental Toxicology Research.Birth defects research · 2026Review
- Factors affecting the umbilical artery Doppler reference values in the second and third trimesters.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Placental mitochondrial calcium uniporter modulates offspring susceptibility to metabolic dysfunction.Molecular metabolism · 2025Article
- A Narrative Review on the Effect of Valproic Acid on the Placenta.Birth defects research · 2025Review
- Thyroid Hormones in Early Pregnancy and Birth Weight: A Retrospective Study.Biomedicines · 2025Article
- Children's birth weight and the risk of general obesity and central obesity in primary school children: a 4-year longitudinal study.Frontiers in public health · 2025Article
- Effect of nano curcumin administration on IL-6 expression in placental organs and fetal weight exposed to stress during pregnancy in mice.Open veterinary journal · 2024Article
- Exploring the Father's Role in Determining Neonatal Birth Weight: A Narrative Review.Medicina (Kaunas, Lithuania) · 2024Review
- Maternal metabolic profiling across body mass index groups: An exploratory longitudinal study.Acta obstetricia et gynecologica Scandinavica · 2024Article
- A Comparative Cross-sectional Study on Prevalence of Low Birth Weight and its Anticipated Risk Factors.Global pediatric health · 2023Article
- Effect of high-fructose consumption in pregnancy on the bone growth of offspring rats.Frontiers in nutrition · 2023Article
- Ferumoxytol dynamic contrast enhanced magnetic resonance imaging identifies altered placental cotyledon perfusion in rhesus macaques†.Biology of reproduction · 2022Article
- Sleep quality is associated with the weight of newborns after in vitro fertilization (IVF)/intra-cytoplasmic sperm injection (ICSI).Sleep & breathing = Schlaf & Atmung · 2022Article
- Maternal body mass index and placental weight: a role for fetal insulin, maternal insulin and leptin.Journal of endocrinological investigation · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMaternal nutritional and metabolic factors influence the developmental environment of the fetus. Virtually any nutritional factor in the maternal blood has to pass the placental membranes to reach the fetal blood. Placental weight is a commonly used measure to summarize placental growth and function. Placental weight is an independent determinant of fetal growth and birthweight and modifies the associations between maternal metabolic factors and fetal growth. We hypothesized that maternal factors known to be related to fetal growth, newborn size and body composition are determinants of placental weight and that effects of maternal metabolic factors on placental weight differ between the genders.
methodsThe STORK study is a prospective longitudinal study including 1031 healthy pregnant women of Scandinavian heritage with singleton pregnancies. Maternal determinants (parity, body mass index, gestational weight gain and fasting plasma glucose) of placental weight were explored by linear regression models, stratified by fetal sex.
resultsParity, maternal BMI, gestational weight gain and fasting glucose had positive effects on placental weight. There was a sex specific effect in these associations. Fasting glucose was significantly associated with placental weight in females but not in males.
conclusionMaternal factors known to influence fetal growth, birthweight and neonatal body composition are determinants of placental weight. The effect of maternal factors on placental weight is influenced by sex as illustrated in the relation between maternal glucose and placental weight.
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