Evidence map›Paper›PMID 24516075›Full record

ArticleInternational journal of STD & AIDS2014

Evaluation of syndromic management of sexually transmitted infections within the Kisumu Incidence Cohort Study.

Fredrick Odhiambo Otieno, Richard Ndivo, Simon Oswago, Johnson Ondiek, Sherri Pals, Eleanor McLellan-Lemal, Robert T Chen, Wairimu Chege, Kristen Mahle Gray

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in International journal of STD & AIDS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 4 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 4 syntheses or guidelines pooled it, 55 citations in OpenAlex.

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  16. Clinical Performance of Cas13a-based Point-of-Care Lateral Flow Assay for DetectingmedRxiv : the preprint server for health sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Fredrick Odhiambo OtienoCentre for Global Health Research, Kenya Medical Research Institute (KEMRI)/CDC Program, Kisumu, Kenya FOtieno@kemricdc.org.
Richard NdivoCentre for Global Health Research, Kenya Medical Research Institute (KEMRI)/CDC Program, Kisumu, Kenya.
Simon OswagoCentre for Global Health Research, Kenya Medical Research Institute (KEMRI)/CDC Program, Kisumu, Kenya.
Johnson OndiekCentre for Global Health Research, Kenya Medical Research Institute (KEMRI)/CDC Program, Kisumu, Kenya.
Sherri PalsCenters for Disease Control and Prevention, Office of Infectious Diseases, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Division of HIV/AIDS Prevention, Atlanta, GA, USA.
Eleanor McLellan-LemalCenters for Disease Control and Prevention, Office of Infectious Diseases, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Division of HIV/AIDS Prevention, Atlanta, GA, USA.
Robert T ChenCenters for Disease Control and Prevention, Office of Infectious Diseases, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Division of HIV/AIDS Prevention, Atlanta, GA, USA.
Wairimu ChegeCenters for Disease Control and Prevention, Office of Infectious Diseases, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Division of HIV/AIDS Prevention, Atlanta, GA, USA.
Kristen Mahle GrayCenters for Disease Control and Prevention, Office of Infectious Diseases, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Division of HIV/AIDS Prevention, Atlanta, GA, USA.
Kenya Medical Research Institute · KECenters for Disease Control and Prevention · USNational Center for HIV/AIDS Viral Hepatitis STD and TB Prevention · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

While laboratory aetiological diagnosis is considered the gold standard for diagnosis and management of sexually transmitted infections (STIs), syndromic management has been presented as a simplified and affordable approach for STI management in limited resource settings. STI signs and symptoms were collected using staff-administered computer-assisted personal interview and audio computer-assisted self-interview. Participants underwent a medical examination and laboratory testing for common STIs. The performance of syndromic management was assessed on the agreement between interviewing methods as well as accurate diagnosis. We screened 846 participants, of whom 88 (10.4%) received syndromic STI diagnosis while 272 (32.2%) received an aetiological diagnosis. Agreement between syndromic and aetiological diagnoses was very poor (overall kappa = 0.09). The most prevalent STI was herpes simplex virus type 2 and the percentage of persons with any STI was higher among women (48.6%) than men (15.6%, p < 0.0001). Agreement between audio computer-assisted self-interview and computer-assisted personal interview interviewing methods for syndromic diagnosis of STIs ranged from poor to good. Our findings suggest that syndromic management of STIs is not a sufficient tool for STI diagnosis in this setting; development and improvement of STI diagnostic capabilities through laboratory confirmation is needed in resource-limited settings.

Indexed as

AdolescentAdultDisease ManagementFemaleHIV InfectionsHumansIncidenceInterviews as TopicKenyaMalePhysical ExaminationPrevalenceSelf CareSex DistributionSexually Transmitted DiseasesSocioeconomic FactorsdiagnosisKenyaKisumusexually transmitted infectionSTIssyndromic management

Identifiers

PMID24516075
PMCPMC4586058
OpenAlexW2125888977

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.