Evidence map›Paper›PMID 24515952›Full record

ArticleMagnetic resonance in medicine2015

Accelerated and navigator-gated look-locker imaging for cardiac T1 estimation (ANGIE): Development and application to T1 mapping of the right ventricle.

Bhairav B Mehta, Xiao Chen, Kenneth C Bilchick, Michael Salerno, Frederick H Epstein

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Review
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  8. FASt single-breathhold 2D multislice myocardial TJournal of magnetic resonance imaging : JMRI · 2020
    Article
  9. Article
  10. Review
  11. Article
  12. Advanced imaging in pulmonary hypertension: emerging techniques and applications.The international journal of cardiovascular imaging · 2019
    Review
  13. Article
  14. Article
  15. Review
  16. Towards accurate and precise TMagma (New York, N.Y.) · 2018
    Review
  17. Association between left ventricular mechanics and diffuse myocardial fibrosis in patients with repaired Tetralogy of Fallot: a cross-sectional study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2017
    Article
  18. Article
  19. T1-refBlochi: high resolution 3D post-contrast T1 myocardial mapping based on a single 3D late gadolinium enhancement volume, Bloch equations, and a reference T1.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2017
    Article
  20. Simultaneous multislice imaging for native myocardial TMagnetic resonance in medicine · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bhairav B MehtaDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.
Xiao ChenDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.
Kenneth C BilchickDepartment of Cardiology, University of Virginia, Charlottesville, Virginia, USA.
Michael SalernoDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.
Frederick H EpsteinDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.

Funding

MRI of Myocardial Function in Post-Infarct Knockout MiceR01EB001763 · NIBIB · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI EPSTEIN, FREDERICK H · 2003 to 2020
$5.4M
Quantitative Adenosine Stress CMR with Spiral Pulse SequencesK23HL112910 · NHLBI · UNIVERSITY OF VIRGINIA · PI SALERNO, MICHAEL · 2012 to 2016
$789k
Cardiac Magnetic Resonance Imaging and Cardiac Resynchronization TherapyK23HL094761 · NHLBI · UNIVERSITY OF VIRGINIA · PI BILCHICK, KENNETH C · 2009 to 2013
$676k
NHLBI NIH HHS K23 HL094761NHLBI NIH HHS K23 HL112910NHLBI NIH HHS K23 HL112910-02NIBIB NIH HHS R01 EB 001763NIBIB NIH HHS R01 EB001763
6 · The paper itself

Abstract

purposeTo develop a method for high-resolution cardiac T1 mapping.

methodsA new method, accelerated and navigator-gated look-locker imaging for cardiac T1 estimation (ANGIE), was developed. An adaptive acquisition algorithm that accounts for the interplay between navigator gating and undersampling patterns well-suited for compressed sensing was used to minimize scan time. Computer simulations, phantom experiments, and imaging of the left ventricle (LV) were used to optimize and evaluate ANGIE. ANGIE's high spatial resolution was demonstrated by T1 mapping of the right ventricle (RV). Comparisons were made to modified Look-Locker imaging (MOLLI).

resultsRetrospective reconstruction of fully sampled datasets demonstrated the advantages of the adaptive algorithm. For the LV, ANGIE measurements of T1 were in good agreement with MOLLI. For the RV, ANGIE achieved a spatial resolution of 1.2 × 1.2 mm(2) with a scan time of 157 ± 53 s per slice, and measured RV T1 values of 980 ± 96 ms versus 1076 ± 157 ms for lower-resolution MOLLI. ANGIE provided lower intrascan variation in the RV T1 estimate compared with MOLLI (P < 0.05).

conclusionANGIE enables high-resolution cardiac T1 mapping in clinically reasonable scan times. ANGIE opens the prospect of quantitative T1 mapping of thin cardiovascular structures such as the RV wall.

Indexed as

AlgorithmsAdultCardiac-Gated Imaging TechniquesFemaleHeart VentriclesHumansImage EnhancementImage Interpretation, Computer-AssistedMagnetic Resonance Imaging, CineMaleReproducibility of ResultsSensitivity and Specificitycardiac MRIcompressed sensingMOLLInavigator gatingright ventricleT1 mapping

Identifiers

PMID24515952
PMCPMC4128906

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.