ArticleSmall (Weinheim an der Bergstrasse, Germany)2014
Near infrared light-triggered drug generation and release from gold nanoparticle carriers for photodynamic therapy.
Article in Small (Weinheim an der Bergstrasse, Germany), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed.
- Gold nanoparticles functionalised with vancomycin enhance antibacterial activity and inhibit Streptococcus pneumoniae adherence and invasion in alveolar cells.The Journal of antibiotics · 2025Article
- Non-Innocent Ligands as Mediators for Visible-Light-Initiated Element-Carbon Bond Homolysis in Main Group Chemistry.Angewandte Chemie (International ed. in English) · 2025Review
- Photodynamic Treatment of Human Breast and Prostate Cancer Cells Using Rose Bengal-Encapsulated Nanoparticles.Molecules (Basel, Switzerland) · 2023Article
- Monodisperse Gold Nanoparticles: A Review on Synthesis and Their Application in Modern Medicine.International journal of molecular sciences · 2022Review
- Development of Bio-Functionalized, Raman Responsive, and Potentially Excretable Gold Nanoclusters.Nanomaterials (Basel, Switzerland) · 2021Article
- Core-shell nanostructures: a simplest two-component system with enhanced properties and multiple applications.Environmental geochemistry and health · 2021Review
- Biomimetic oxygen delivery nanoparticles for enhancing photodynamic therapy in triple-negative breast cancer.Journal of nanobiotechnology · 2021Article
- Thermo-responsive polymer encapsulated gold nanorods for single continuous wave laser-induced photodynamic/photothermal tumour therapy.Journal of nanobiotechnology · 2021Article
- Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials.Chemical reviews · 2020Article
- Optimizing a Novel Au-Grafted Lipid Nanoparticle Through Chelation Chemistry for High Photothermal Biologic Activity.Journal of pharmaceutical sciences · 2020Article
- A Review on the Synthesis and Functionalization of Gold Nanoparticles as a Drug Delivery Vehicle.International journal of nanomedicine · 2020Review
- Ultrasmall gold nanoparticles in cancer diagnosis and therapy.Theranostics · 2020Review
- Nanoscale Metal-Organic Frameworks for Phototherapy of Cancer.Coordination chemistry reviews · 2019Article
- S,S-Chiral Linker Induced U Shape with a Syn-facial Sensitizer and Photocleavable Ethene Group.Photochemistry and photobiology · 2019Article
- Hyaluronic Acid Grafted Nanoparticles of a Platinum(II)-Silicon(IV) Phthalocyanine Conjugate for Tumor and Mitochondria-Targeted Photodynamic Therapy in Red Light.Journal of materials chemistry. B · 2018Article
- Functional Polymer Nanocarriers for Photodynamic Therapy.Pharmaceuticals (Basel, Switzerland) · 2018Review
- Near-Infrared Photoactivatable Nitric Oxide Donors with Integrated Photoacoustic Monitoring.Journal of the American Chemical Society · 2018Article
- Defining the conditional basis of silicon phthalocyanine near-IR ligand exchange.Physical chemistry chemical physics : PCCP · 2018Article
- Prostate-Specific Membrane Antigen Targeted Gold Nanoparticles for Theranostics of Prostate Cancer.ACS nano · 2018Article
- Nanotechnology for Cancer Therapy Based on Chemotherapy.Molecules (Basel, Switzerland) · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
A photoprecursor Pc 227 is covalently bound onto gold nanoparticles (Au NPs) to produce the known photodynamic therapy (PDT) drug Pc 4 upon 660 nm photoirradiation. The photochemical formation of the photoproduct Pc 4 is identified by spectroscopy, chromatography, and mass spectrometry and its PDT efficacy is equal to Pc 4 when administered non-covalently by Au NPs, with the added benefit of improved covalent delivery and targeted NIR-triggered release from the covalent Pc 227-Au NP conjugate, while during transport the attached Pc 227 is quenched by the Au NP and PDT inactivated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.