Evidence map›Paper›PMID 24515551›Full record

ArticleJAMA internal medicine2014

Hospital variation in the use of noninvasive cardiac imaging and its association with downstream testing, interventions, and outcomes.

Kyan C Safavi, Shu-Xia Li, Kumar Dharmarajan, Arjun K Venkatesh, Kelly M Strait, Haiqun Lin, Timothy J Lowe, Reza Fazel, Brahmajee K Nallamothu, Harlan M Krumholz

Abstract read
In one paragraph

Article in JAMA internal medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
11.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 109 citations in OpenAlex.

  1. Trial
  2. The HEART Pathway Randomized Controlled Trial One-year Outcomes.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2019
    Trial
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  17. Prevention after acute coronary syndrome the 'less is more' philosophy.European heart journal supplements : journal of the European Society of Cardiology · 2020
    Article
  18. Article
  19. Article
  20. Provocative testing for low-risk chest pain patients, must we continue?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Kyan C SafaviYale University School of Medicine, New Haven, Connecticut.
Shu-Xia LiCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Connecticut3Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Kumar DharmarajanCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Connecticut4Division of Cardiology, Columbia University Medical Center, New York, New York.
Arjun K VenkateshDepartment of Emergency Medicine, Yale University School of Medicine, New Haven, Connecticut6Robert Wood Johnson Foundation Clinical Scholars Program, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Kelly M StraitCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Connecticut3Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Haiqun LinCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Connecticut7Department of Biostatistics, Yale School of Public Health, New Haven, Connecticut.
Timothy J LowePremier Inc, Charlotte, North Carolina.
Reza FazelDivision of Cardiology, Department of Medicine, Emory University School of Medicine and Emory Clinical Cardiovascular Research Institute, Atlanta, Georgia.
Brahmajee K NallamothuVeterans Affairs Health Services Research and Development Center of Excellence, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan11Department of Internal Medicine, University of Michigan, Ann Arbor 12Center for Healthcare Outcomes and Poli.
Harlan M KrumholzCenter for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Connecticut3Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut6Robert Wood Johnson Foundation Cli.
Yale University · USYale New Haven Hospital · USEmory Clinic · USPremier Research Group · USVA Ann Arbor Healthcare System · US

Funding

YALE UNIVERSITY CLINICAL AND TRANSLATIONAL SCIENCE AWARD PROGRAMUL1RR024139 · NCRR · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2006 to 2011
$56.8M
POSTDOCTORAL TRAINING IN CARDIOVASCULAR DISEASET32HL007854 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Marwah Abdalla, Michael Argenziano · 1996 to 2026
$14.7M
Center for Cardiovascular Outcomes Research at Yale UniversityU01HL105270 · NHLBI · YALE UNIVERSITY · PI CURTIS, JEPTHA PELHAM, KRUMHOLZ, HARLAN MARC · 2010 to 2013
$5.8M
NCRR NIH HHS UL1 RR024139NCRR NIH HHS UL1 RR024139-06SNHLBI NIH HHS HL007854NHLBI NIH HHS T32 HL007854NHLBI NIH HHS U01 HL105270NHLBI NIH HHS U01 HL105270-04
6 · The paper itself

Abstract

IMPORTANCE Current guidelines allow substantial discretion in use of noninvasive cardiac imaging for patients without acute myocardial infarction (AMI) who are being evaluated for ischemia. Imaging use may affect downstream testing and outcomes. OBJECTIVE To characterize hospital variation in use of noninvasive cardiac imaging and the association of imaging use with downstream testing, interventions, and outcomes. DESIGN, SETTING, AND PARTICIPANTS Cross-sectional study of hospitals using 2010 administrative data from Premier, Inc, including patients with suspected ischemia on initial evaluation who were seen in the emergency department, observation unit, or inpatient ward; received at least 1 cardiac biomarker test on day 0 or 1; and had a principal discharge diagnosis for a common cause of chest discomfort, a sign or symptom of cardiac ischemia, and/or a comorbidity associated with coronary disease. We excluded patients with AMI. MAIN OUTCOMES AND MEASURES At each hospital, the proportion of patients who received noninvasive imaging to identify cardiac ischemia and the subsequent rates of admission, coronary angiography, and revascularization procedures. RESULTS We identified 549,078 patients at 224 hospitals. The median (interquartile range) hospital noninvasive imaging rate was 19.8% (10.9%-27.7%); range, 0.2% to 55.7%. Median hospital imaging rates by quartile were Q1, 6.0%; Q2, 15.9%; Q3, 23.5%; Q4, 34.8%. Compared with Q1, Q4 hospitals had higher rates of admission (Q1, 32.1% vs Q4, 40.0%), downstream coronary angiogram (Q1, 1.2% vs Q4, 4.9%), and revascularization procedures (Q1, 0.5% vs Q4, 1.9%). Hospitals in Q4 had a lower yield of revascularization for noninvasive imaging (Q1, 7.6% vs Q4, 5.4%) and for angiograms (Q1, 41.2% vs Q4, 38.8%). P <.001 for all comparisons. Readmission rates to the same hospital for AMI within 2 months were not different by quartiles (P = .51). Approximately 23% of variation in imaging use was attributable to the behavior of individual hospitals. CONCLUSIONS AND RELEVANCE Hospitals vary in their use of noninvasive cardiac imaging in patients with suspected ischemia who do not have AMI. Hospitals with higher imaging rates did not have substantially different rates of therapeutic interventions or lower readmission rates for AMI but were more likely to admit patients and perform angiography.

Indexed as

HospitalizationBiomarkersCardiovascular DiseasesCross-Sectional StudiesDiagnostic ImagingFemaleHumansMaleOutcome and Process Assessment, Health CarePractice Patterns, Physicians'United StatesBiomarkers

Identifiers

PMID24515551
PMCPMC5459406
OpenAlexW2016158403

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.