Evidence map›Paper›PMID 24514034›Full record

ReviewCurrent opinion in anaesthesiology2014

Delirium in the cardiac surgical ICU.

Charles H Brown

Registry-linked trialOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current opinion in anaesthesiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03729011 (Delirium Reduction by Volatile Anesthesia in Cardiac Surgery), which is not on this map. Cited by 80 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 10 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03729011 phase4completednot on this mapstarted 2019, after this paper: background citation

Delirium Reduction by Volatile Anesthesia in Cardiac Surgery: Prospective, Randomized, Single-blinded Study

TypeinterventionalSponsorMeshalkin Research Institute of Pathology of CirculationRan2019 to 2024Enrolled405ConditionsDeliriumArmsVolatile agent, Propofol
3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 10 syntheses or guidelines pooled it, 192 citations in OpenAlex.

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  5. DEX, Delirium and Dilemma.Brazilian journal of cardiovascular surgery · 2023
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20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Charles H BrownDepartment of Anesthesiology and Critical Care Medicine, The John Hopkins School of Medicine, Baltimore, Maryland, USA.

Funding

The impact of impaired cerebral autoregulation on postoperative deliriumR03AG042331 · NIA · JOHNS HOPKINS UNIVERSITY · PI BROWN, CHARLES HUGH · 2012 to 2013
$158k
NIA NIH HHS R03 AG042331
6 · The paper itself

Abstract

purpose of reviewEvidence is emerging that delirium is associated with both short-term and long-term morbidity and mortality. This review highlights the epidemiology, outcomes, prevention and treatment strategies associated with delirium after cardiac surgery. RECENT

findingsThe incidence of delirium after cardiac surgery is estimated to be 26-52%, with a significant percentage being hypoactive delirium. It is clear that without an appropriate structured test for delirium, the incidence of delirium will be underrecognized clinically. Delirium after cardiac surgery is associated with poor outcomes, including increased long-term mortality, increased risk of stroke, poor functional status, increased hospital readmissions and substantial cognitive dysfunction for 1 year following surgery. The effectiveness of prophylactic antipsychotics to reduce the risk of delirium is controversial, with data from recent small studies in noncardiac surgery potentially showing a benefit. Although antipsychotic medications are often used to treat delirium, the evidence that antipsychotics in cardiac surgery patients reduce duration of delirium or improve long-term outcomes following delirium is poor. SUMMARY: Clinicians in the ICU must recognize the impact of delirium in predicting long-term outcomes for patients. Further research is needed in determining interventions that will be effective in preventing and treating delirium in cardiac surgical setting.

Indexed as

Antipsychotic AgentsCardiac Surgical ProceduresDeliriumHumansIncidenceIntensive Care UnitsAntipsychotic Agents

Identifiers

PMID24514034
PMCPMC4156112
OpenAlexW1979703816

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.