Evidence map›Paper›PMID 24513715›Full record

ReviewHuman vaccines & immunotherapeutics2014

Listeria monocytogenes: a promising vehicle for neonatal vaccination.

Zach Z Liang, Ashley M Sherrid, Anu Wallecha, Tobias R Kollmann

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Human vaccines & immunotherapeutics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. HarnessingArchives of Razi Institute · 2025
    Review
  2. Article
  3. [Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023
    Article
  4. Innate and Adaptive Immune Responses duringMicrobiology spectrum · 2019
    Article
  5. Vaccine responses in newborns.Seminars in immunopathology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zach Z LiangDivision of Infectious and Immunological Diseases; Department of Pediatrics; University of British Columbia; Child and Family Research Institute; Vancouver, BC Canada.
Ashley M SherridDivision of Infectious and Immunological Diseases; Department of Pediatrics; University of British Columbia; Child and Family Research Institute; Vancouver, BC Canada.
Anu WallechaAdvaxis Inc.; Princeton, NJ USA.
Tobias R KollmannDivision of Infectious and Immunological Diseases; Department of Pediatrics; University of British Columbia; Child and Family Research Institute; Vancouver, BC Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccination as a medical intervention has proven capable of greatly reducing the suffering from childhood infectious disease. However, newborns and infants in particular are age groups for whom adequate vaccine-mediated protection is still largely lacking. With the challenges that the neonatal immune system faces and the required highest level of stringency for safety, designing vaccines for early life in general and the newborn in particular poses great difficulty. Nevertheless, recent advances in our understanding of neonatal immunity and its responses to vaccines and adjuvants suggest that neonatal vaccination is a task fully within reach. Among the most promising developments in neonatal vaccination is the use of Listeria monocytogenes (Lm) as a delivery platform. In this review, we will outline key properties of Lm that make it such an ideal neonatal and early life vaccine vehicle, and also discuss potential constraints of Lm as a vaccine delivery platform.

Indexed as

Drug CarriersGenetic VectorsHumansListeria monocytogenesVaccinationVaccines, SyntheticDrug CarriersVaccines, Syntheticadjuvantantigen deliveryattenuationbirthListeria monocytogenesneonatesafetyvaccination

Identifiers

PMID24513715
PMCPMC4896561

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.