Evidence map›Paper›PMID 24513656›Full record

ReviewCurrent opinion in microbiology2014

The involvement of transport proteins in transcriptional and metabolic regulation.

Ake Västermark, Milton H Saier

Abstract readReview
In one paragraph

Review in Current opinion in microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A single point mutation in theFrontiers in microbiology · 2024
    Article
  5. Article
  6. Fosfomycin resistance mechanisms inFrontiers in cellular and infection microbiology · 2023
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Genomic Analysis of the EndophyticFrontiers in microbiology · 2021
    Article
  12. Article
  13. Review
  14. What bacteria want.Environmental microbiology · 2018
    Review
  15. Review
  16. Review
  17. Article
  18. Transposon-mediated directed mutation in bacteria and eukaryotes.Frontiers in bioscience (Landmark edition) · 2017
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ake VästermarkDepartment of Molecular Biology, University of California at San Diego, La Jolla, CA 92093-0116, United States.
Milton H SaierDepartment of Molecular Biology, University of California at San Diego, La Jolla, CA 92093-0116, United States. Electronic address: msaier@ucsd.edu.
University of California, San Diego · US

Funding

TransportPDB: Center for the X-ray Structure Determination of Human TransportersU54GM094610 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI SAIER, MILTON H. · 2010 to 2014
$12.2M
The Transporter Classification Database (TCDB)R01GM077402 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SAIER, MILTON H. · 2006 to 2021
$4.7M
NIGMS NIH HHS GM077402-05A1NIGMS NIH HHS GM 094610-01NIGMS NIH HHS R01 GM077402NIGMS NIH HHS U54 GM094610
6 · The paper itself

Abstract

Transport proteins have sometimes gained secondary regulatory functions that influence gene expression and metabolism. These functions allow communication with the external world via mechanistically distinctive signal transduction pathways. In this brief review we focus on three transport systems in Escherichia coli that control and coordinate carbon, exogenous hexose-phosphate and phosphorous metabolism. The transport proteins that play central roles in these processes are: first, the phosphoenolpyruvate (PEP)-dependent phosphotransferase system (PTS), second, the glucose-6-phosphate receptor, UhpC, and third, the phosphate-specific transporter, PstSABC, respectively. While the PTS participates in multiple complex regulatory processes, three of which are discussed here, UhpC and the Pst transporters exemplify differing strategies.

Indexed as

Gene Expression Regulation, BacterialTranscription, GeneticCarbonEscherichia coliEscherichia coli ProteinsHexosesMembrane Transport ProteinsPhosphorusCarbonEscherichia coli ProteinsHexosesMembrane Transport ProteinsPhosphorus

Identifiers

PMID24513656
PMCPMC3999241
OpenAlexW1966105194

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.