Evidence map›Paper›PMID 24513152›Full record

Trial reportNeuroImage2014

The evolution of a disparity decision in human visual cortex.

Benoit R Cottereau, Justin M Ales, Anthony M Norcia

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in NeuroImage, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. [Abnormal spontaneous brain functional activity in adult patients with amblyopia: a resting-state functional magnetic resonance imaging study].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2022
    Article
  3. Article
  4. Ultra-High-Field Neuroimaging Reveals Fine-Scale Processing for 3D Perception.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Representation of Maximally Regular Textures in Human Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016
    Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Benoit R CottereauUniversité de Toulouse, UPS, Centre de Recherche Cerveau et Cognition, France; CNRS, CerCo, Toulouse, France. Electronic address: cottereau@cerco.ups-tlse.fr.
Justin M AlesSchool of Psychology and Neuroscience, St Mary's Quad, South Street, University of St Andrews, St Andrews KY16 9JP, UK.
Anthony M NorciaDepartment of Psychology, Jordan Hall, Building 01-420, Stanford University, 450 Serra Mall, Stanford, CA 94305, USA.

Funding

Disparity processing in visual cortexR01EY018875 · NEI · STANFORD UNIVERSITY · PI NORCIA, ANTHONY M · 2008 to 2021
$4.6M
NEI NIH HHS R01 EY018875
6 · The paper itself

Abstract

We used fMRI-informed EEG source-imaging in humans to characterize the dynamics of cortical responses during a disparity-discrimination task. After the onset of a disparity-defined target, decision-related activity was found within an extended cortical network that included several occipital regions of interest (ROIs): V4, V3A, hMT+ and the Lateral Occipital Complex (LOC). By using a response-locked analysis, we were able to determine the timing relationships in this network of ROIs relative to the subject's behavioral response. Choice-related activity appeared first in the V4 ROI almost 200 ms before the button press and then subsequently in the V3A ROI. Modeling of the responses in the V4 ROI suggests that this area provides an early contribution to disparity discrimination. Choice-related responses were also found after the button-press in ROIs V4, V3A, LOC and hMT+. Outside the visual cortex, choice-related activity was found in the frontal and temporal poles before the button-press. By combining the spatial resolution of fMRI-informed EEG source imaging with the ability to sort out neural activity occurring before, during and after the behavioral manifestation of the decision, our study is the first to assign distinct functional roles to the extra-striate ROIs involved in perceptual decisions based on disparity, the primary cue for depth.

Indexed as

CuesAdultAgedBrain MappingChoice BehaviorElectroencephalographyFemaleHumansJudgmentMagnetic Resonance ImagingMaleMiddle AgedNerve NetVision DisparityVisual CortexYoung AdultBinocular visionDecision makingDisparity processingEEGNeural imaging

Identifiers

PMID24513152
PMCPMC4336795

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.