Trial reportResuscitation2014
The impact of peri-shock pause on survival from out-of-hospital shockable cardiac arrest during the Resuscitation Outcomes Consortium PRIMED trial.
Trial report in Resuscitation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- 2025 Korean Guidelines for Cardiopulmonary Resuscitation: Part 4. Adult advanced life support.Clinical and experimental emergency medicine · 2026Guideline
- 2020 Korean Guidelines for Cardiopulmonary Resuscitation. Part 4. Adult advanced life support.Clinical and experimental emergency medicine · 2021Guideline
- The System-Wide Effect of Real-Time Audiovisual Feedback and Postevent Debriefing for In-Hospital Cardiac Arrest: The Cardiopulmonary Resuscitation Quality Improvement Initiative.Critical care medicine · 2015Trial
- Singapore Advanced Cardiac Life Support Guidelines 2026.Singapore medical journal · 2026Article
- Realtime detection of spontaneous circulation in humans during cardiopulmonary resuscitation using a continuous hands-free carotid Doppler: a pilot study.Resuscitation plus · 2025Article
- Comparison of Cardiopulmonary Resuscitation Quality in a Simulated Model: At Incident Scene vs During EMS Transport.The western journal of emergency medicine · 2025Article
- A retrospective 'target trial emulation' comparing amiodarone and lidocaine for adult out-of-hospital cardiac arrest resuscitation.Resuscitation · 2025Article
- The association between initial defibrillation dose and outcomes following adult out-of-hospital cardiac arrest resuscitation: A retrospective, multi-agency study.Resuscitation · 2025Observational
- The outcome of out-of-hospital cardiac arrest based on the etiology of cardiac arrest; A scoping review.PloS one · 2025Article
- Association Between Chest Compression Pause Duration and Survival After Pediatric In-Hospital Cardiac Arrest.Circulation · 2024Article
- Lung tissue injury and hemodynamic effects of ventilations synchronized or unsynchronized to continuous chest compressions in a porcine cardiac arrest model.Resuscitation plus · 2024Article
- An effort to reduce chest compression pauses during automated external defibrillator use among laypeople: A randomized partially blinded controlled trial.Resuscitation plus · 2023Article
- Differences in Automated External Defibrillator Types in Out-of-Hospital Cardiac Arrest Treated by Police First Responders.Journal of cardiovascular development and disease · 2023Article
- Article
- [Effects of automated external defibrillators on hands-off intervals in lay rescuers].Notfall & rettungsmedizin · 2022Article
- Impact of different methods to activate the pediatric mode in automated external defibrillators by laypersons - A randomized controlled simulation study.Resuscitation plus · 2022Article
- Management Decisions: The Effectiveness and Size of the Emergency Medical Team.International journal of environmental research and public health · 2022Article
- Inverse Association Between Bystander Use of Audiovisual Feedback From an Automated External Defibrillator and Return of Spontaneous Circulation.Journal of the American Heart Association · 2022Article
- Pulse rate as an alternative, real-time feedback indicator for chest compression rate: a porcine model of cardiac arrest.Journal of clinical monitoring and computing · 2021Article
- Can hospital adult code-teams and individual members perform high-quality CPR? A multicenter simulation-based study incorporating an educational intervention with CPR feedback.Resuscitation plus · 2021Article
Corrections and comments
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Authors and funding
17 authors.
Funding
Abstract
backgroundPrevious research has demonstrated significant relationships between peri-shock pause and survival to discharge from out-of-hospital shockable cardiac arrest (OHCA).
objectiveTo determine the impact of peri-shock pause on survival from OHCA during the ROC PRIMED randomized controlled trial.
methodsWe included patients in the ROC PRIMED trial who suffered OHCA between June 2007 and November 2009, presented with a shockable rhythm and had CPR process data for at least one shock. We used multivariable logistic regression to determine the association between peri-shock pause duration and survival to hospital discharge.
resultsAmong 2006 patients studied, the median (IQR) shock pause duration was: pre-shock pause 15s (8, 22); post-shock pause 6s (4, 9); and peri-shock pause 22.0 s (14, 31). After adjusting for Utstein predictors of survival as well as CPR quality measures, the odds of survival to hospital discharge were significantly higher for patients with pre-shock pause <10s (OR: 1.52, 95% CI: 1.09, 2.11) and peri-shock pause <20s (OR: 1.82, 95% CI: 1.17, 2.85) when compared to patients with pre-shock pause ≥ 20s and peri-shock pause ≥ 40s. Post-shock pause was not significantly associated with survival to hospital discharge. Results for neurologically intact survival (Modified Rankin Score ≤ 3) were similar to our primary outcome.
conclusionsIn patients with cardiac arrest presenting in a shockable rhythm during the ROC PRIMED trial, shorter pre- and peri-shock pauses were significantly associated with higher odds of survival. Future cardiopulmonary education and technology should focus on minimizing all peri-shock pauses.
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