ReviewCurrent topics in developmental biology2014
Postembryonic organogenesis of the digestive tube: why does it occur in worms and sea cucumbers but fail in humans?
Review in Current topics in developmental biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Article
- Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium.bioRxiv : the preprint server for biology · 2024Article
- Evidence of interactions among apoptosis, cell proliferation, and dedifferentiation in the rudiment during whole-organ intestinal regeneration in the sea cucumber.Developmental biology · 2024Article
- EchinoDB: an update to the web-based application for genomic and transcriptomic data on echinoderms.BMC genomic data · 2022Article
- A pan-metazoan concept for adult stem cells: the wobbling Penrose landscape.Biological reviews of the Cambridge Philosophical Society · 2022Article
- The Role of the Microbiota in Regeneration-Associated Processes.Frontiers in cell and developmental biology · 2021Review
- Article
- The mesentery as the epicenter for intestinal regeneration.Seminars in cell & developmental biology · 2019Review
- Radial Glia in Echinoderms.Developmental neurobiology · 2019Review
- Characterization of the intestinal microbiota of the sea cucumber Holothuria glaberrima.PloS one · 2019Article
- Expression of stem cell factors in the adult sea cucumber digestive tube.Cell and tissue research · 2017Article
- The sea cucumber genome provides insights into morphological evolution and visceral regeneration.PLoS biology · 2017Article
- Gut-spilling in chordates: evisceration in the tropical ascidian Polycarpa mytiligera.Scientific reports · 2015Article
- Expression of pluripotency factors in echinoderm regeneration.Cell and tissue research · 2015Article
- Transcriptomic changes during regeneration of the central nervous system in an echinoderm.BMC genomics · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
We provide an integrative view of mechanisms that enable regeneration of the digestive tube in various animal models, including vertebrates, tunicates, echinoderms, insects, and flatworms. Two main strategies of regeneration of the endodermal luminal (mucosal) epithelium have evolved in metazoans. One of them involves proliferation of resident epithelial cells, while the other relies on recruitment of cells from extramucosal sources. In any of these two scenarios, either pluri-/multipotent stem cells or specialized differentiated cells can be used as the starting material. Posttraumatic visceral regeneration shares some common mechanisms with normal embryonic development as well as with organ homeostatic maintenance, but there are signaling pathways and/or cellular pools that are specific to the regenerative phenomena. Comparative analysis of the literature suggests that mammals share with spontaneously regenerating animals many of the regeneration-related adaptations and are able to efficiently repair components of their digestive tube at the level of individual tissues, but fail to do so at the whole-organ scale. We review what might cause this failure in the context of the current state of knowledge about various regenerative models.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.