SynthesisHeadache2014
Obesity and headache: part I--a systematic review of the epidemiology of obesity and headache.
Synthesis in Headache, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
73 citing papers in PubMed, 7 syntheses or guidelines pooled it, 123 citations in OpenAlex.
- Adults with excess weight or obesity, but not with overweight, report greater pain intensities than individuals with normal weight: a systematic review and meta-analysis.Frontiers in endocrinology · 2024Pooled it
- Obesity and pain: a systematic review.International journal of obesity (2005) · 2020Pooled it
- Preoperative risk factors for postoperative complications in endoscopic pituitary surgery: a systematic review.Pituitary · 2018Pooled it
- Pooled it
- Adipokines and Migraine: A Systematic Review.Headache · 2016Pooled it
- Migraine and body mass index categories: a systematic review and meta-analysis of observational studies.The journal of headache and pain · 2015Pooled it
- Adiponectin and migraine: systematic review of clinical evidence.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2014Pooled it
- Is Sigstad's score really capable of detecting post-surgical late dumping syndrome?Langenbeck's archives of surgery · 2024Trial
- Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial.BMJ (Clinical research ed.) · 2021Trial
- Behavioral Weight Loss Intervention for Migraine: A Randomized Controlled Trial.Obesity (Silver Spring, Md.) · 2018Trial
- Headache in Idiopathic Intracranial Hypertension: Findings From the Idiopathic Intracranial Hypertension Treatment Trial.Headache · 2017Trial
- Objectively measured physical activity in obese women with and without migraine.Cephalalgia : an international journal of headache · 2015Trial
- The prevalence of primary headache disorders and their associated factors among nursing staff in North China.The journal of headache and pain · 2015Trial
- Does low and heavy load resistance training affect musculoskeletal pain in overweight and obese women? Secondary analysis of a randomized controlled trial.Brazilian journal of physical therapyTrial
- Cardiometabolic parameters and novel hematological indices in women with migraine.Journal of medical biochemistry · 2026Article
- New Adjuvant Therapies for Obesity-Related Disorders Associated with Meta-Neuroinflammation.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Investigating predictors of pain events during trials of knee osteoarthritis: A post-hoc analysis of two phase III trials.Osteoarthritis and cartilage open · 2026Article
- Article
- Headache and GLP-1 receptor agonists: when medications are therapeutic and when they contribute to the symptom.Arquivos de neuro-psiquiatria · 2025Review
- Association of visceral adiposity index and chronic pain in US adults: a cross-sectional study.Scientific reports · 2025Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
Individually, both obesity and headache are conditions associated with a substantial personal and societal impact. Recent data support that obesity is comorbid with headache in general and migraine specifically, as well as with certain secondary headache conditions such as idiopathic intracranial hypertension. In the current manuscript, we first briefly review the epidemiology of obesity and common primary and secondary headache disorders individually. This is followed by a systematic review of the general population data evaluating the association between obesity and headache in general, and then obesity and migraine and tension-type headache disorders. Finally, we briefly discuss the data on the association between obesity and a common secondary headache disorder that is associated with obesity, idiopathic intracranial hypertension. Taken together, these data suggest that it is important for clinicians and patients to be aware of the headache/migraine-obesity association, given that it is potentially modifiable. Hypotheses for mechanisms of the obesity-migraine association and treatment considerations for overweight and obese headache sufferers are discussed in the companion manuscript, as part II of this topic.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.