Evidence map›Paper›PMID 24512265›Full record

ArticleJournal of midwifery & women's health

Outcomes of nulliparous women with spontaneous labor onset admitted to hospitals in preactive versus active labor.

Jeremy L Neal, Jane M Lamp, Jacalyn S Buck, Nancy K Lowe, Shannon L Gillespie, Sharon L Ryan

Open access · bronzeAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Journal of midwifery & women's health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 70 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The Pathophysiology of Labor Dystocia: Theme with Variations.Reproductive sciences (Thousand Oaks, Calif.) · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Adverse Perinatal Outcomes Predicted by Prenatal Maternal Stress Among U.S. Women at the COVID-19 Pandemic Onset.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Observational
  16. Article
  17. Review
  18. Labor Pattern Among Primigravida in Local Population.Journal of obstetrics and gynaecology of India · 2018
    Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jeremy L Neal
Jane M Lamp
Jacalyn S Buck
Nancy K Lowe
Shannon L Gillespie
Sharon L Ryan
The Ohio State University · USUniversity of Colorado Denver · USRiverside Methodist Hospital · US

Funding

University of Iowa Clinical and Translational Science Program (TL1)UL1RR025755 · NCRR · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2008 to 2011
$26.3M
The Ohio State University Center for clinical and Translational ScienceUL1TR001070 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2013 to 2017
$22.6M
Inflammatory markers as predictors of active labor onset among nulliparous womenR03NR011493 · NINR · OHIO STATE UNIVERSITY · PI NEAL, JEREMY L · 2010 to 2011
$152k
Pathways to shortened gestation among Black womenF31NR014605 · NINR · OHIO STATE UNIVERSITY · PI GILLESPIE, SHANNON L. · 2013 to 2015
$86k
Maternal physiological factors influencing labor lengthF31NR010054 · NINR · OHIO STATE UNIVERSITY · PI NEAL, JEREMY L · 2006 to 2008
$66k
NCATS NIH HHS UL1 TR001070NCRR NIH HHS UL1 RR025755NCRR NIH HHS UL1RR025755NINR NIH HHS 1 F31 NR010054NINR NIH HHS F31 NR010054NINR NIH HHS F31 NR014605NINR NIH HHS R03 NR011493NINR NIH HHS R03NR011493
6 · The paper itself

Abstract

introductionThe timing of when a woman is admitted to the hospital for labor care following spontaneous contraction onset may be among the most important decisions that labor attendants make because it can influence care patterns and birth outcomes. The aims of this study were to estimate the percentage of low-risk, nulliparous women at term who are admitted to labor units prior to active labor and to evaluate the effects of the timing of admission (ie, preactive vs active labor) on labor interventions and mode of birth.

methodsData from low-risk, nulliparous women with spontaneous labor onset at term gestation were merged from 2 prospective studies conducted at 3 large Midwestern hospitals. Baseline characteristics, labor interventions, and outcomes were compared between groups using Fisher's exact and Mann-Whitney U tests, as appropriate. Likelihoods for oxytocin augmentation, amniotomy, and cesarean birth were assessed by logistic regression.

resultsOf the sample of 216 low-risk nulliparous women, 114 (52.8%) were admitted in preactive labor and 102 (47.2%) were admitted in active labor. Women who were admitted in preactive labor were more likely to undergo oxytocin augmentation (84.2% and 45.1%, respectively; odds ratio [OR], 6.5; 95% confidence interval [CI], 3.43-12.27) but not amniotomy (55.3% and 61.8%, respectively; OR, 0.8; 95% CI, 0.44-1.32) when compared to women admitted in active labor. The likelihood of cesarean birth was higher for women admitted before active labor onset (15.8% and 6.9%, respectively; OR, 2.6; 95% CI, 1.02-6.37). DISCUSSION: Many low-risk nulliparous women with regular, spontaneous uterine contractions are admitted to labor units before active labor onset, which increases their likelihood of receiving oxytocin and giving birth via cesarean. An evidence-based, standardized approach for labor admission decision making is recommended to decrease inadvertent admissions of women in preactive labor. When active labor cannot be diagnosed with relative certainty, observation before admission to the birthing unit is warranted.

Indexed as

Delivery RoomsLabor OnsetPatient AdmissionAdultCesarean SectionFemaleHumansLogistic ModelsObstetricsOdds RatioOxytocinParityPregnancyProspective StudiesRiskTerm BirthOxytocincesarean sectionlabor onsetnulliparityoxytocin

Identifiers

PMID24512265
PMCPMC4104945
OpenAlexW1976730061

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.