Evidence map›Paper›PMID 24512171›Full record

ArticleJournal of the American Geriatrics Society2014

Delirium risk prediction, healthcare use and mortality of elderly adults in the emergency department.

Maura Kennedy, Richard A Enander, Sarah P Tadiri, Richard E Wolfe, Nathan I Shapiro, Edward R Marcantonio

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 9 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 9 syntheses or guidelines pooled it, 212 citations in OpenAlex.

  1. Pooled it
  2. Guideline
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  4. Risk factors and risk stratification approaches for delirium screening: A Geriatric Emergency Department Guidelines 2.0 systematic review.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2024
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26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Maura KennedyDepartment of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Richard A Enander
Sarah P Tadiri
Richard E Wolfe
Nathan I Shapiro
Edward R Marcantonio
Beth Israel Deaconess Medical Center · US

Funding

Protocolized Care for Early Septic Shock (ProCESS)P50GM076659 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ANGUS, DEREK C · 2006 to 2012
$11.2M
Biology of Tie2 in sepsisR01HL093234 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI PARIKH, SAMIR M · 2008 to 2017
$4.6M
Endothelial Cell Signaling and Microcirculatory Flow in Severe SepsisR01HL091757 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SHAPIRO, NATHAN I · 2008 to 2011
$2.0M
Mid-Career Mentoring Award for Patient-Oriented Research in AgingK24AG035075 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI MARCANTONIO, EDWARD R · 2010 to 2021
$1.9M
Assess Emergency Department Patients Developing Delirium after Hospital AdmissionR03AG040706 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI KENNEDY, MAURA · 2011 to 2012
$174k
NHLBI NIH HHS 5R01HL093234-02NHLBI NIH HHS HL091757NHLBI NIH HHS R01 HL091757NHLBI NIH HHS R01 HL093234NIA NIH HHS 1R03AG040706-01NIA NIH HHS K24 AG035075NIA NIH HHS R03 AG040706NIGMS NIH HHS GM076659NIGMS NIH HHS P50 GM076659
6 · The paper itself

Abstract

objectivesTo create a risk prediction rule for delirium in elderly adults in the emergency department (ED) and to compare mortality and resource use of elderly adults in the ED with and without delirium.

designProspective observational study.

settingUrban tertiary care ED.

participantsIndividuals aged 65 and older presenting for ED care (N = 700). MEASUREMENTS: A trained research assistant performed a structured mental status assessment and attention tests, after which delirium was determined using the Confusion Assessment Method. Data were collected on participant demographics, comorbidities, medications, ED course, hospital and intensive care unit (ICU) admission, length of stay, hospital charges, 30-day rehospitalization, and mortality.

resultsNine percent of elderly study participants had delirium. Using logistic regression, a delirium prediction rule consisting of older age, prior stroke or transient ischemic attack, dementia, suspected infection, and acute intracranial hemorrhage was created had good predictive accuracy (area under the receiver operating characteristic curve = 0.77). Admitted participants with ED delirium had longer median lengths of stay (4 vs 2 days) and were more likely to require ICU admission (13% vs 6%) and to be discharged to a new long-term care facility (37% vs 9%) than those without. In all participants, ED delirium was associated with higher 30-day mortality (6% vs 1%) and 30-day readmission (27% vs 13%).

conclusionThis risk prediction rule may help identify a group of individuals in the ED at high risk of developing delirium who should undergo screening, but it requires external validation. Identification of delirium in the ED may enable physicians to implement strategies to decrease delirium duration and avoid inappropriate discharge of individuals with acute delirium, improving outcomes.

Indexed as

Emergency Service, HospitalAgedAged, 80 and overDeliriumDelivery of Health CareFemaleFollow-Up StudiesGeriatric AssessmentHumansIncidenceLength of StayMaleMassachusettsMental Status ScheduleProspective StudiesRisk Factorsdeliriumemergency medicinegeriatrics

Identifiers

PMID24512171
PMCPMC3959285
OpenAlexW1967487362

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.