Evidence map›Paper›PMID 24511547›Full record

ReviewBioMed research international2014

Phytochemical and pharmacological properties of Gymnema sylvestre: an important medicinal plant.

Pragya Tiwari, B N Mishra, Neelam S Sangwan

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02370121 (Effect of Gymnema Sylvestre Administration on Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion), which is not on this map. Cited by 64 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 2 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02370121 phase2completednot on this map

Effect of Gymnema Sylvestre Administration on Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion

TypeinterventionalSponsorUniversity of GuadalajaraRan2013 to 2015Enrolled24ConditionsMetabolic SyndromeArmsPlacebo, Gymnema Sylvestre
3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 2 syntheses or guidelines pooled it, 228 citations in OpenAlex.

  1. The effect of flavonoids on the doxorubicin efficacy in cancer treatment.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Pooled it
  2. Pooled it
  3. Comparative Effects ofNutrients · 2024
    Trial
  4. Review
  5. International journal of molecular sciences · 2026
    Review
  6. Article
  7. Antidiabetic effects ofWorld journal of experimental medicine · 2026
    Article
  8. Review
  9. Article
  10. Review
  11. Plants (Basel, Switzerland) · 2025
    Article
  12. Article
  13. Frontiers in plant science · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Food science & nutrition · 2024
    Review
  18. Article
  19. Use of Buzz Buttons to Illustrate Taste Perception Principles in a Sensation and Perception Laboratory Exercise.Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2024
    Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Pragya TiwariMetabolic and Structural Biology Department, Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), P.O. CIMAP, Lucknow 226015, India.
B N MishraDepartment of Biotechnology, Gautam Buddh Technical University, Lucknow, Uttar Pradesh 226021, India.
Neelam S SangwanMetabolic and Structural Biology Department, Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP), P.O. CIMAP, Lucknow 226015, India.
Central Institute of Medicinal and Aromatic Plants · INDr. A.P.J. Abdul Kalam Technical University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gymnema sylvestre (Asclepiadaceae), popularly known as "gurmar" for its distinct property as sugar destroyer, is a reputed herb in the Ayurvedic system of medicine. The phytoconstituents responsible for sweet suppression activity includes triterpene saponins known as gymnemic acids, gymnemasaponins, and a polypeptide, gurmarin. The herb exhibits a broad range of therapeutic effects as an effective natural remedy for diabetes, besides being used for arthritis, diuretic, anemia, osteoporosis, hypercholesterolemia, cardiopathy, asthma, constipation, microbial infections, indigestion, and anti-inflammatory. G. sylvestre has good prospects in the treatment of diabetes as it shows positive effects on blood sugar homeostasis, controls sugar cravings, and promotes regeneration of pancreas. The herbal extract is used in dietary supplements since it reduces body weight, blood cholesterol, and triglyceride levels and holds great prospects in dietary as well as pharmacological applications. This review explores the transition of a traditional therapeutic to a modern contemporary medication with an overview of phytochemistry and pharmacological activities of the herb and its phytoconstituents.

Indexed as

Gymnema sylvestrePlant ExtractsPlants, MedicinalAnimalsAnti-Infective AgentsAntineoplastic AgentsHumansHypoglycemic AgentsMedicine, AyurvedicMiceProtective AgentsRatsAnti-Infective AgentsAntineoplastic AgentsHypoglycemic AgentsPlant ExtractsProtective Agents

Identifiers

PMID24511547
PMCPMC3912882
OpenAlexW2076870960

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.