Evidence map›Paper›PMID 24511327›Full record

ArticlePolymer chemistry2014

A quantitative recipe for engineering protein polymer nanoparticles.

S Mohd Janib, M Pastuszka, S Aluri, Z Folchman-Wagner, P-Y Hsueh, P Shi, Yi-An, H Cui, J A Mackay

Open access · greenAbstract read
In one paragraph

Article in Polymer chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 88 citations in OpenAlex.

  1. Pooled it
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  13. Liquid-cell transmission electron microscopy for imaging of thermosensitive recombinant polymers.Journal of controlled release : official journal of the Controlled Release Society · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

S Mohd JanibDepartment of Pharmacology and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA; 90033-9121.
M PastuszkaDepartment of Pharmacology and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA; 90033-9121.
S AluriDepartment of Pharmacology and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA; 90033-9121.
Z Folchman-WagnerDepartment of Pharmacology and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA; 90033-9121.
P-Y HsuehDepartment of Pharmacology and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA; 90033-9121.
P ShiDepartment of Pharmacology and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA; 90033-9121.
Yi-AnDepartment of Chemical and Biomolecular Engineering, Johns Hopkins University Baltimore, MD 21218 USA.
H CuiDepartment of Chemical and Biomolecular Engineering, Johns Hopkins University Baltimore, MD 21218 USA.
J A MackayDepartment of Pharmacology and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA; 90033-9121.
University of Southern California · USJohns Hopkins University · US

Funding

USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORTP30CA014089 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Fumito Ito · 1985 to 2026
$181.4M
USC RESEARCH CENTER FOR LIVER DISEASES: PILOT PROGRAMSP30DK048522 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KAPLOWITZ, NEIL · 1995 to 2020
$21.8M
A rapid, reversible switch for controlling intracellular traffickingR21EB012281 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MACKAY, JOHN ANDREW · 2010 to 2011
$438k
NCI NIH HHS P30 CA014089NIBIB NIH HHS R21 EB012281NIDDK NIH HHS P30 DK048522
6 · The paper itself

Abstract

Protein polymers can assemble switchable nanostructures with emerging applications as biomaterials and nanomedicines. For example, above a critical micelle temperature (CMT) some elastin-like polypeptide (ELP) diblock copolymers assemble spherical nanoparticles, which may modulate cellular internalization and

Indexed as

block copolymerElastin-like polypeptidemicellesself-assembly

Identifiers

PMID24511327
PMCPMC3916011
OpenAlexW2124159149

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.