ReviewTheScientificWorldJournal2014
Shedding light on a new treatment for diabetic wound healing: a review on phototherapy.
Review in TheScientificWorldJournal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Mechanisms of photobiomodulation therapy in treating and preventing antineoplastic-induced oral mucositis: a systematic review.Acta cirurgica brasileira · 2025Pooled it
- Photobiomodulation: systematic review and meta-analysis of the most used parameters in the resolution diabetic foot ulcers.Lasers in medical science · 2021Pooled it
- Treatment of diabetic foot ulcers in a frail population with severe co-morbidities using at-home photobiomodulation laser therapy: a double-blind, randomized, sham-controlled pilot clinical study.Lasers in medical science · 2022Trial
- A randomized controlled trial comparing helium-neon laser therapy and infrared laser therapy in patients with diabetic foot ulcer.Lasers in medical science · 2018Trial
- The effects of exercise training associated with low-level laser therapy on biomarkers of adipose tissue transdifferentiation in obese women.Lasers in medical science · 2018Trial
- Low-level laser therapy (LLLT) associated with aerobic plus resistance training to improve inflammatory biomarkers in obese adults.Lasers in medical science · 2015Trial
- Comparative Evaluation ofFoods (Basel, Switzerland) · 2026Article
- Photobiomodulation and Low-Level Laser Therapy as Complementary Strategies in Diabetes Treatment.International journal of molecular sciences · 2026Review
- Diabetic Dermopathies as Predictive Markers of Cardiovascular and Renal Complications: A Narrative Review.Journal of clinical medicine · 2025Review
- Cell migration in diabetic wound healing: Molecular mechanisms and therapeutic strategies (Review).International journal of molecular medicine · 2025Review
- Curcumin and Papain-Loaded Liposomal Natural Latex Dressings with Phototherapy: A Synergistic Approach to Diabetic Wound Healing.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Therapies and delivery systems for diabetic wound care: current insights and future directions.Frontiers in pharmacology · 2025Review
- Development and application of the RaphaAmerican journal of translational research · 2024Article
- Dose-response relationship of photobiomodulation therapy and oxidative stress markers in healing dynamics of diabetic neuropathic ulcers in Wistar rats.Journal of diabetes and metabolic disorders · 2023Article
- Photobiomodulation at 660 nm Stimulates In Vitro Diabetic Wound Healing via the Ras/MAPK Pathway.Cells · 2023Article
- [Research progress of infrared light promoting wound healing].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2022Review
- The Effects of Blue Light on Human Fibroblasts and Diabetic Wound Healing.Life (Basel, Switzerland) · 2022Review
- Amitriptyline-Based Biodegradable PEG-PLGA Self-Assembled Nanoparticles Accelerate Cutaneous Wound Healing in Diabetic Rats.Pharmaceutics · 2022Article
- Chitosan-Based Microparticle EncapsulatedTurkish journal of pharmaceutical sciences · 2022Article
- Photobiomodulation at 830 nm Stimulates Migration, Survival and Proliferation of Fibroblast Cells.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Impaired wound healing is a common complication associated with diabetes with complex pathophysiological underlying mechanisms and often necessitates amputation. With the advancement in laser technology, irradiation of these wounds with low-intensity laser irradiation (LILI) or phototherapy, has shown a vast improvement in wound healing. At the correct laser parameters, LILI has shown to increase migration, viability, and proliferation of diabetic cells in vitro; there is a stimulatory effect on the mitochondria with a resulting increase in adenosine triphosphate (ATP). In addition, LILI also has an anti-inflammatory and protective effect on these cells. In light of the ever present threat of diabetic foot ulcers, infection, and amputation, new improved therapies and the fortification of wound healing research deserves better prioritization. In this review we look at the complications associated with diabetic wound healing and the effect of laser irradiation both in vitro and in vivo in diabetic wound healing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.