Evidence map›Paper›PMID 24511261›Full record

ArticleMateria socio-medica2013

The effect of psychoactive substances (drugs) on the presence and frequency of oral Candida species and Candida dubliniensis.

Sanja Hadzic, Amira Dedic, Mirjana Gojkov-Vukelic, Nermana Mehic-Basara, Mirsada Hukic, Mirela Babic, Edina Beslagic

Abstract read
In one paragraph

Article in Materia socio-medica, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Mucocutaneous Manifestations of Recreational Drug Use.American journal of clinical dermatology · 2024
    Review
  3. Article
  4. Article
  5. IDCases · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. Case Report:Frontiers in neurology · 2020
    Article
  10. Frequency ofAdvanced biomedical research · 2020
    Article
  11. Article
  12. Molecular characterization ofCurrent medical mycology · 2018
    Article
  13. Knowledge, attitude and practice of dental professionals towards substance use.Journal of International Society of Preventive & Community Dentistry
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sanja HadzicDepartment of Oral Medicine and Periodontology, Faculty of Dentistry, University of Sarajevo, Bosnia and Herzegovina.
Amira DedicDepartment of Oral Medicine and Periodontology, Faculty of Dentistry, University of Sarajevo, Bosnia and Herzegovina.
Mirjana Gojkov-VukelicDepartment of Oral Medicine and Periodontology, Faculty of Dentistry, University of Sarajevo, Bosnia and Herzegovina.
Nermana Mehic-BasaraInstitute for Alcoholism and Other Addictions, Sarajevo Canton, Sarajevo, Bosnia and Herzegovina.
Mirsada HukicInstitute of Microbiology, Parasitology and Immunology of the University Clinical Center in Sarajevo, Sarajevo, Bosnia and Herzegovina.
Mirela BabicInstitute of Microbiology, Parasitology and Immunology of the University Clinical Center in Sarajevo, Sarajevo, Bosnia and Herzegovina.
Edina BeslagicDepartment of Microbiology, Faculty of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

the goalThe goal of this study was to determine the effect of psychoactive substances (drugs) on the presence and frequency of oral Candida species and Candida dubliniensis. MATERIALS AND

methodsFor the purpose of achieving the set goals, we chose a sample. Sixty bed-ridden patients from the Institute for Alcoholism and Other Addictions in Sarajevo Canton, both males and females between 18 and 60 years of age, were included in the research and assigned to two different groups (alcohol addicts and opiate addicts). After extensive anamnesis and a clinical examination, samples of oral epithelia were taken for microbiological identification. Two confirmatory methods were used for the identification of Candida species: the blastesis test and cultivation in a chromatophilic medium (Chrom agar). A yeast assimilation test (API test) was used for the identification of non-albicans Candida. A separate test was used to identify Candida dubliniensis (PAL agar).

resultsThe results of the microbiological analysis confirmed the frequency of Candida albicans (43%) in psychoactive substance addicts, as well as an increase in non-albicans Candida regardless of the type of addiction (34%). The presence of Candida dubliniensis was proven in psychoactive substance addicts (23%) and it was confirmed that the frequency of bacterial adherence of Candida dubliniensis is directly proportional to the duration of the drug-addiction.

conclusionThe abuse of psychoactive substances has an effect on the frequency of albicans and non-albicans species of oral Candida. Based on the findings, we have concluded that psychoactive substances (opiates and alcohol) lead to an increase in oral Candida dubliniensis regardless of the type of addictions.

Indexed as

Candida dubliniensis.oral Candida speciesPsychoactive substances (drugs)

Identifiers

PMID24511261
PMCPMC3914741

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.