Evidence map›Paper›PMID 24511260›Full record

ArticleEuropean journal of organic chemistry2013

Synthesis of a Comprehensive Polyprenol Library for Evaluation of Bacterial Enzyme Lipid Substrate Specificity.

Baolin Wu, Robert Woodward, Liuqing Wen, Xuan Wang, Guohui Zhao, Peng George Wang

Abstract read
In one paragraph

Article in European journal of organic chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Synthesis and shift-reagent-assisted full NMR assignment of bacterial (ZChemical communications (Cambridge, England) · 2017
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Baolin WuThe Center for Therapeutics and Diagnostics (CDT), Department of Chemistry, Georgia State University, Atlanta, GA 30303, USA, , Homepage: http://chemistry.gsu.edu/faculty/PWang/
Robert WoodwardDepartment of Chemistry and Biochemistry, University of Mount Union, Alliance, OH 44601, USA.
Liuqing WenThe Center for Therapeutics and Diagnostics (CDT), Department of Chemistry, Georgia State University, Atlanta, GA 30303, USA, , Homepage: http://chemistry.gsu.edu/faculty/PWang/
Xuan WangThe Center for Therapeutics and Diagnostics (CDT), Department of Chemistry, Georgia State University, Atlanta, GA 30303, USA, , Homepage: http://chemistry.gsu.edu/faculty/PWang/
Guohui ZhaoThe Center for Therapeutics and Diagnostics (CDT), Department of Chemistry, Georgia State University, Atlanta, GA 30303, USA, , Homepage: http://chemistry.gsu.edu/faculty/PWang/
Peng George WangThe Center for Therapeutics and Diagnostics (CDT), Department of Chemistry, Georgia State University, Atlanta, GA 30303, USA, , Homepage: http://chemistry.gsu.edu/faculty/PWang/
Georgia State University · USUniversity of Mount Union · US

Funding

Biosynthesis of PolysaccharidesR01GM085267 · NIGMS · OHIO STATE UNIVERSITY · PI WANG, PENG GEORGE · 2009 to 2017
$2.4M
NIGMS NIH HHS R01 GM085267
6 · The paper itself

Abstract

Polyprenols, a type of universal glycan lipid carrier, play important roles for glycan bio-assembly in wide variety of living systems. Chemical synthesis of natural polyisoprenols such as undecaprenol and dolichols, but especially their homologs, could serves as a powerful molecular tool to dissect and define the functions of enzymes involved in glycan biosynthesis. In this paper, we report an efficient and reliable method to construct this type of hydrophoic molecule through a base-mediated iterative coupling approach using a key bifunctional (

Indexed as

Enzyme substrate specificityLipopolysaccharidePolyprenol

Identifiers

PMID24511260
PMCPMC3915775
OpenAlexW1550125628

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.