ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2014
Quality of life along the diabetes continuum: a cross-sectional view of health-related quality of life and general health status in middle-aged and older Finns.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Assessing the Effectiveness of Digital Health Behavior Strategies on Type 2 Diabetes Management: Systematic Review and Network Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Depressive symptoms decrease health-related quality of life of patients with coronary artery disease and diabetes: a 12-month follow up study in primary care.Scandinavian journal of primary health care · 2023Trial
- Digitally Supported Lifestyle Intervention to Prevent Type 2 Diabetes Through Healthy Habits: Secondary Analysis of Long-Term User Engagement Trajectories in a Randomized Controlled Trial.Journal of medical Internet research · 2022Trial
- Cost-effectiveness of prevention program for type 2 diabetes mellitus in high risk patients in the Republic of Srpska, Bosnia and Herzegovina.The Libyan journal of medicine · 2025Article
- Glycemic status and health-related quality of life (HRQOL) in populations at risk of diabetes in two Latin American cities.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Impaired health-related quality of life due to elevated risk of developing diabetes: A cross-sectional study in Indonesia.PloS one · 2023Article
- Health-related quality of life for normal glycaemia, prediabetes and type 2 diabetes mellitus: Cross-sectional analysis of the ADDITION-PRO study.Diabetic medicine : a journal of the British Diabetic Association · 2022Article
- Health-related quality of life (HRQoL) in a population at risk of type 2 diabetes: a cross-sectional study in two Latin American cities.Health and quality of life outcomes · 2021Article
- Impact of Chronic Pain on Patients' Quality of Life: A Comparative Mixed-Methods Study.Journal of patient experience · 2019Article
- Health-Related Quality of Life in Tehran Lipid and Glucose Study.International journal of endocrinology and metabolism · 2018Review
- Comparison of health-related quality of Life (HRQOL) among patients with pre-diabetes, diabetes and normal glucose tolerance, using the 15D-HRQOL questionnaire in Greece: the DEPLAN study.BMC endocrine disorders · 2018Article
- BoostMe accurately predicts DNA methylation values in whole-genome bisulfite sequencing of multiple human tissues.BMC genomics · 2018Article
- The cost-effectiveness of interventions targeting lifestyle change for the prevention of diabetes in a Swedish primary care and community based prevention program.The European journal of health economics : HEPAC : health economics in prevention and care · 2017Article
- Differential expression analysis for RNAseq using Poisson mixed models.Nucleic acids research · 2017Article
- The relationship between hypertension and health-related quality of life: adjusted by chronic pain, chronic diseases, and life habits in the general middle-aged population in Japan.Environmental health and preventive medicine · 2016Article
- The genetic regulatory signature of type 2 diabetes in human skeletal muscle.Nature communications · 2016Article
- Article
- Predicting Self-Rated Health in Diabetes and Chronic Heart Failure - A Multiple Mediation Model.Frontiers in public health · 2015Article
- Health-related quality of life for pre-diabetic states and type 2 diabetes mellitus: a cross-sectional study in Västerbotten Sweden.Health and quality of life outcomes · 2014Article
- Phosphodiesterase-5 inhibitors for erectile dysfunction in patients with diabetes mellitus: A systematic review and meta-analysis of randomized controlled trials.Indian journal of endocrinology and metabolismReview
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo examine the general health status and health-related quality of life (HRQOL) along the diabetes continuum of middle-aged and older Finns, and to determine the glucose metabolism stage by which the HRQOL has decreased noticeably.
methodsThe cross-sectional sample consisted of 920 persons aged 51-75 from the general population in a single municipality in a rural area of Eastern Finland. Data were adjusted for age, sex, smoking history, current alcohol consumption, employment and marital status. The HRQOL and health status were evaluated using two preference-based HRQOL instruments, 15D and SF-6D, and one health profile instrument, 36-Item Short Form Health Survey (SF-36).
resultsIndividuals with impaired glucose tolerance (IGT) and type 2 diabetes had noticeably low mean SF-6D, 15D and general health status. The decrease in overall HRQOL was mainly due to a decline in the physical dimensions of HRQOL. The adjusted odds ratios (95% CI) for having noticeably low HRQOL on SF-6D, 15D and general health dimension of SF-36 associated with IGT were 1.95 (1.18-3.25), 1.35 (0.84-2.18) and 2.00 (1.21-3.29), respectively.
conclusionsThe progression along the diabetes continuum was significantly associated with a decrease in HRQOL and health status. Furthermore, the data indicate that when a person is detected to have IGT, the HRQOL and general health status have already diminished noticeably. The prevailing evidence suggests that detection and intervention before a patient develops IGT is essential in order to minimize the loss of quality of life and quality-adjusted life years.
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