Evidence map›Paper›PMID 24510550›Full record

ReviewPhotosynthesis research2015

Toward a photosynthetic microbial platform for terpenoid engineering.

Fiona K Davies, Robert E Jinkerson, Matthew C Posewitz

Abstract readReview
PubMed Publisher
In one paragraph

Review in Photosynthesis research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 90 citations in OpenAlex.

  1. Review
  2. Review
  3. Perspectives of cyanobacterial cell factories.Photosynthesis research · 2024
    Review
  4. EngineeringmLife · 2023
    Article
  5. Engineered production of isoprene from the model green microalgaMetabolic engineering communications · 2023
    Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Strategies for enhancing terpenoids accumulation in microalgae.Applied microbiology and biotechnology · 2021
    Review
  12. Endophytes: the novel sources for plant terpenoid biosynthesis.Applied microbiology and biotechnology · 2021
    Review
  13. Photosynthetic Conversion of COFrontiers in bioengineering and biotechnology · 2021
    Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Fiona K DaviesDepartment of Chemistry and Geochemistry, Colorado School of Mines, Golden, CO, 80401, USA, fbentley@mines.edu.
Robert E Jinkerson
Matthew C Posewitz
Colorado School of Mines · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant terpenoids are among the most diverse group of naturally-occurring organic compounds known, and several are used in contemporary consumer products. Terpene synthase enzymes catalyze complex rearrangements of carbon skeleton precursors to yield thousands of unique chemical structures that range in size from the simplest five carbon isoprene unit to the long polymers of rubber. Such chemical diversity has established plant terpenoids as valuable commodity chemicals with applications in the pharmaceutical, neutraceutical, cosmetic, and food industries. More recently, terpenoids have received attention as a renewable alternative to petroleum-derived fuels and as the building blocks of synthetic biopolymers. However, the current plant- and petrochemical-based supplies of commodity terpenoids have major limitations. Photosynthetic microorganisms provide an opportunity to generate terpenoids in a renewable manner, employing a single consolidated host organism that is able to use solar energy, H2O and CO2 as the primary inputs for terpenoid biosynthesis. Advances in synthetic biology have seen important breakthroughs in microbial terpenoid engineering, traditionally via fermentative pathways in yeast and Escherichia coli. This review draws on the knowledge obtained from heterotrophic microbial engineering to propose strategies for the development of microbial photosynthetic platforms for industrial terpenoid production. The importance of utilizing the wealth of genetic information provided by nature to unravel the regulatory mechanisms of terpenoid biosynthesis is highlighted.

Indexed as

BiofuelsAlkyl and Aryl TransferasesCyanobacteriaMetabolic EngineeringMicroalgaePhotosynthesisTerpenesAlkyl and Aryl TransferasesBiofuelsTerpenesterpene synthase

Identifiers

PMID24510550
OpenAlexW2046568531

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.