Evidence map›Paper›PMID 24510526›Full record

ReviewAAPS PharmSciTech2014

Nanoemulsions in translational research-opportunities and challenges in targeted cancer therapy.

Srinivas Ganta, Meghna Talekar, Amit Singh, Timothy P Coleman, Mansoor M Amiji

Abstract readReview
In one paragraph

Review in AAPS PharmSciTech, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Nanoemulsions in Skin Cancer Therapy: A Promising Frontier.Current pharmaceutical biotechnology · 2025
    Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Plant Based Extract Oil-Based Nano emulsions: Impact on Human Melanoma Cell Line.Asian Pacific journal of cancer prevention : APJCP · 2024
    Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Srinivas GantaNemucore Medical Innovations, Inc., Worcester, Massachusetts, 01608, USA.
Meghna Talekar
Amit Singh
Timothy P Coleman
Mansoor M Amiji

Funding

Physico-Chemical Nanocharacterization CoreU54CA151881 · NCI · NORTHEASTERN UNIVERSITY · PI TORCHILIN, VLADIMIR P · 2010 to 2014
$12.4M
NCI NIH HHS U54 CA151881NCI NIH HHS U54-CA151881
6 · The paper itself

Abstract

Nanoemulsion dosage form serves as a vehicle for the delivery of active pharmaceutical ingredients and has attracted great attention in drug delivery and pharmacotherapy. In particular, nanoemulsions act as an excellent vehicle for poorly aqueous soluble drugs, which are otherwise difficult to formulate in conventional dosage forms. Nanoemulsions are submicron emulsions composed of generally regarded as safe grade excipients. Particle size at the nanoscale and larger surface area lead to some very interesting physical properties that can be exploited to overcome anatomical and physiological barriers associated in drug delivery to the complex diseases such as cancer. Along these lines, nanoemulsions have been engineered with specific attributes such as size, surface charge, prolonged blood circulation, target specific binding ability, and imaging capability. These attributes can be tuned to assist in delivering drug/imaging agents to the specific site of interest, based on active and passive targeting mechanisms. This review focuses on the current state of nanoemulsions in the translational research and its role in targeted cancer therapy. In addition, the production, physico-chemical characterization, and regulatory aspects of nanoemulsion are addressed.

Indexed as

Drug CarriersMolecular Targeted TherapyNanomedicineNanoparticlesTranslational Research, BiomedicalAnimalsAntineoplastic AgentsChemistry, PharmaceuticalContrast MediaDiagnostic ImagingEmulsionsHumansLipidsNeoplasmsRadiopharmaceuticalsTechnology, PharmaceuticalAntineoplastic AgentsContrast MediaDrug CarriersEmulsionsLipidsRadiopharmaceuticals

Identifiers

PMID24510526
PMCPMC4037485

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.