Evidence map›Paper›PMID 24510500›Full record

ArticleEuropean journal of immunology2014

Gimap and T cells: a matter of life or death.

Thomas Ciucci, Rémy Bosselut

Open access · bronzeAbstract read
In one paragraph

Article in European journal of immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Two-stage CD8Nature communications · 2025
    Article
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  16. Review
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  19. [Subcellular localization of GTPase of immunity-associated protein 2].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Thomas CiucciLaboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Rémy Bosselut
National Institutes of Health · US

Funding

Genetic Analysis of T-cell DifferentiationZIABC010671 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI BOSSELUT, REMY · 2009 to 2025
$34.3M
Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

GTPase immune-associated proteins (Gimap) genes encode evolutionarily conserved GTP-binding proteins that are preferentially expressed in immune cells. Specific members have been shown to be involved in lymphocyte development, or are associated with inflammatory and autoimmune diseases. However, the function of these proteins remains poorly understood, both at the cellular and molecular levels. A new study in this issue of the European Journal of Immunology [Eur. J. Immunol. 2014. 44: 561-572] points to the distinct but partly overlapping functions of two members of this family, Gimap3 and Gimap5, and offers new insight into their potential functions in T cells.

Indexed as

AnimalsAutoimmune DiseasesGTP-Binding ProteinsGTP PhosphohydrolasesHumansInflammationLymphocytesT-LymphocytesGTP-Binding ProteinsGTP Phosphohydrolasesauto-immunityBcl-2GTPase immune-associated proteinslymphopeniaT-cell survival

Identifiers

PMID24510500
PMCPMC4005041
OpenAlexW1493161971

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.