Evidence map›Paper›PMID 24510291›Full record

ArticleCurrent protocols in microbiology2013

DNA immunization.

Shixia Wang, Shan Lu

Abstract read
In one paragraph

Article in Current protocols in microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shixia WangUniversity of Massachusetts Medical School, Worcester, Massachusetts.
Shan LuUniversity of Massachusetts Medical School, Worcester, Massachusetts.

Funding

Optimizing the immunogenicity of next generation polyvalent HIV vaccine formulatiU19AI082676 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LU, SHAN · 2009 to 2016
$15.8M
Variation in HIV-1 R5 Envs: Consequences for tropism, neutralization & vaccinesP01AI082274 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LU, SHAN · 2009 to 2013
$9.7M
Polyvalent DNA Plus Protein HIV VaccinesR01AI065250 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LU, SHAN · 2006 to 2010
$1.9M
Multi-gene Subunit Vaccine Platform Against Y. pestisU01AI078073 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LU, SHAN · 2008 to 2011
$1.7M
IMMUNOGENICITY OF HIV DNA VACCINER29AI040337 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LU, SHAN · 1997 to 2001
$166k
NIAID NIH HHS P01 AI082274NIAID NIH HHS P01AI082274NIAID NIH HHS R01AI065250NIAID NIH HHS R29AI40337NIAID NIH HHS U01 AI078073NIAID NIH HHS U01AI078073NIAID NIH HHS U19 AI082676NIAID NIH HHS U19AI082676
6 · The paper itself

Abstract

DNA immunization was discovered in early 1990s, and its use has been expanded from vaccine studies to a broader range of biomedical research areas, such as the generation of high-quality polyclonal and monoclonal antibodies as research reagents. In this unit, three common DNA immunization methods are described: needle injection, electroporation, and gene gun. In addition, several common considerations related to DNA immunization are discussed.

Indexed as

AnimalsBiolisticsElectroporationHumansImmunizationInjectionsVaccines, DNAVaccines, DNADNA vaccineelectroporationgene gunimmunization

Identifiers

PMID24510291
PMCPMC3920301

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.