ArticleProtoplasma2014
Effect of cadmium stress on inductive enzymatic and nonenzymatic responses of ROS and sugar metabolism in multiple shoot cultures of Ashwagandha (Withania somnifera Dunal).
Article in Protoplasma, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 110 citations in OpenAlex.
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- Redox-linked hormetic responses of Withania coagulans (Stocks) Dunal to Mn, Zn, and Fe supplementation in vitro.BMC plant biology · 2026Article
- Calcium-dependent regulation of antioxidant metabolism in maize seedlings under cadmium stress.Open life sciences · 2026Article
- Cd Stress Response in Emmer Wheat (Biology · 2025Article
- The Role of Polyphenols in Abiotic Stress Tolerance and Their Antioxidant Properties to Scavenge Reactive Oxygen Species and Free Radicals.Antioxidants (Basel, Switzerland) · 2025Review
- Antioxidant Activity and Photosynthesis Efficiency inMolecules (Basel, Switzerland) · 2023Article
- Bioaccumulation and physiological changes in the fruiting body of Agaricus bisporus (Large) sing in response to cadmium.Scientific reports · 2022Article
- Gamma ray-induced tissue responses and improved secondary metabolites accumulation in Catharanthus roseus.Applied microbiology and biotechnology · 2022Article
- Evaluating the Accumulation of Antioxidant and Macro- and Trace Elements in Vaccinium myrtillus L.Biological trace element research · 2022Article
- Concurrent herbivory and metal accumulation: The outcome for plants and herbivores.Plant-environment interactions (Hoboken, N.J.) · 2022Article
- Article
- Cadmium toxicity in medicinal plants: An overview of the tolerance strategies, biotechnological and omics approaches to alleviate metal stress.Frontiers in plant science · 2022Review
- Metabolic alterations elicited by Cd and Zn toxicity in Zea mays with the association of Claroideoglomus claroideum.Ecotoxicology (London, England) · 2022Article
- Chemical Elicitors-Induced Variation in Cellular Biomass, Biosynthesis of Secondary Cell Products, and Antioxidant System in Callus Cultures ofMolecules (Basel, Switzerland) · 2021Article
- Neuroprotective effects ofHeliyon · 2021Article
- Ecophysiological, anatomical, and apigenin changes due to uptake and accumulation of cadmium in Matricaria chamomilla L. flowers in hydroponics.Environmental science and pollution research international · 2021Article
- Toxic Metals (As, Cd, Ni, Pb) Impact in the Most Common Medicinal Plant (International journal of environmental research and public health · 2021Article
- Phytoremediation efficiency of Helianthus annuus L. for reclamation of heavy metals-contaminated industrial soil.Environmental science and pollution research international · 2020Article
- Cadmium chloride (CdCl3 Biotech · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Withania somnifera is one of the most important medicinal plant and is credited with various pharmacological activities. In this study, in vitro multiple shoot cultures were exposed to different concentrations (5-300 μM) of cadmium (Cd) as cadmium sulphate to explore its ability to accumulate the heavy metal ion and its impact on the metabolic status and adaptive responses. The results showed that supplemental exposure to Cd interfered with N, P, and K uptake creating N, P, and K deficiency at higher doses of Cd that also caused stunting of growth, chlorosis, and necrosis. The study showed that in vitro shoots could markedly accumulate Cd in a concentration-dependent manner. Enzymatic activities and isozymic pattern of catalase, ascorbate peroxidase, guaiacol peroxidase, peroxidase, glutathione-S-transferase, glutathione peroxidase, monodehydroascorbate reductase, and dehydroascorbate reductase were altered substantially under Cd exposure. Sugar metabolism was also markedly modulated under Cd stress. Various other parameters including contents of photosynthetic pigments, phenolics, tocopherol, flavonoids, reduced glutathione, nonprotein thiol, ascorbate, and proline displayed major inductive responses reflecting their protective role. The results showed that interplay of enzymatic as well as nonenzymatic responses constituted a system endeavor of tolerance of Cd accumulation and an efficient scavenging strategy of its stress implications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.