Evidence map›Paper›PMID 24509184›Full record

ReviewDiagnostic and interventional radiology (Ankara, Turkey)

Genotype-phenotype correlations in hepatocellular adenoma: an update of MRI findings.

Maarten G Thomeer, Mirelle E E Bröker, Quido de Lussanet, Katharina Biermann, Roy S Dwarkasing, Rob de Man, Jan N Ijzermans, Marianne de Vries

Open access · greenAbstract readReview
In one paragraph

Review in Diagnostic and interventional radiology (Ankara, Turkey). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Hepatocellular adenoma: An unsolved diagnostic enigma.World journal of gastroenterology · 2019
    Review
  6. Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Maarten G ThomeerFrom the Departments of Radiology Medical Center Zuiderzee, Lelystad, the Netherlands. m.devries.2@erasmusmc.nl.
Mirelle E E Bröker
Quido de Lussanet
Katharina Biermann
Roy S Dwarkasing
Rob de Man
Jan N Ijzermans
Marianne de Vries
Erasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular adenoma (HCA) is a generally benign liver tumor with the potential for malignancy and bleeding. HCAs are categorized into four subtypes on the basis of genetic and pathological features: hepatocyte nuclear factor 1α-mutated HCA, β-catenin-mutated HCA, inflammatory HCA, and unclassified HCA. Magnetic resonance imaging (MRI) plays an important role in the diagnosis, subtype characterization, and detection of HCA complications; it is also used to differentiate HCA from focal nodular hyperplasia. In this review, we present an overview of the genetic abnormalities, oncogenesis, and typical and atypical MRI findings of specific subtypes of HCA using contrast-enhanced MRI with or without hepatobiliary contrast agents (gadobenate dimeglumine and gadoxetate disodium). We also discuss their different management implications after diagnosis.

Indexed as

Magnetic Resonance ImagingAdenoma, Liver Cellbeta CateninContrast MediaDiagnosis, DifferentialFemaleFocal Nodular HyperplasiaGadoliniumGadolinium DTPAGenotypeHumansImage EnhancementImmunohistochemistryLiverLiver NeoplasmsMalebeta CateninContrast MediaGadoliniumGadolinium DTPAgadolinium ethoxybenzyl DTPA

Identifiers

PMID24509184
PMCPMC4463344
OpenAlexW2165835558

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.