Trial reportDiagnostic and interventional radiology (Ankara, Turkey)
Use of shear wave elastography to differentiate benign and malignant breast lesions.
Trial report in Diagnostic and interventional radiology (Ankara, Turkey). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Comparative Diagnostic Accuracy of Contrast-Enhanced Ultrasound and Shear Wave Elastography in Differentiating Benign and Malignant Lesions: A Network Meta-Analysis.Frontiers in oncology · 2019Pooled it
- Value of shear wave elastography in discriminating malignant and benign breast lesions: A meta-analysis.Medicine · 2017Pooled it
- Trial
- A convolutional attention model for predicting response to chemo-immunotherapy from ultrasound elastography in mouse tumor models.Communications medicine · 2024Article
- Shear-Wave Elastography Gradient Analysis of Newly Diagnosed Breast Tumours: A Critical Analysis.Diagnostics (Basel, Switzerland) · 2024Article
- Optical coherence tomography and shear wave elastography findings in Graves ophthalmopathy.International ophthalmology · 2024Article
- Use of shear-wave elastography to distinguish complex and complicated fibroadenomas from simple fibroadenomas.Diagnostic and interventional radiology (Ankara, Turkey) · 2023Article
- Changes in pectoralis major stiffness and thickness following radiotherapy for breast cancer: A 12-month follow-up case series.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2023Article
- Value of shear wave elastography during second-look breast ultrasonography for suspicious lesions on magnetic resonance imaging.Journal of medical ultrasonics (2001) · 2022Article
- Ultrasonic technologies in imaging and drug delivery.Cellular and molecular life sciences : CMLS · 2021Review
- Application value of conventional ultrasound combined with shear wave elastography in diagnosing triple negative breast cancer.Gland surgery · 2021Article
- Elastic Modulus and Elasticity Ratio of Malignant Breast Lesions with Shear Wave Ultrasound Elastography: Variations with Different Region of Interest and Lesion Size.Diagnostics (Basel, Switzerland) · 2021Article
- Stiffness increases with myofibroblast content and collagen density in mesenchymal high grade serous ovarian cancer.Scientific reports · 2021Article
- Role of "Stiff Rim" sign obtained by shear wave elastography in diagnosis and guiding therapy of breast cancer.International journal of medical sciences · 2021Article
- The role of tissue elasticity in the differential diagnosis of benign and malignant breast lesions using shear wave elastography.BMC cancer · 2020Article
- A Pilot Study: N-Staging Assessment of Shear Wave Elastrography in Small Cervical Lymph Nodes for Nasopharyngeal Carcinoma.Frontiers in oncology · 2020Article
- SONOELASTOGRAPHIC FEATURES OF HIGH-RISK BREAST LESIONS AND DUCTAL CARCINOMAActa clinica Croatica · 2019Article
- Shear Wave Elasticity Measurements of Three-Dimensional Cancer Cell Cultures Using Laser Speckle Contrast Imaging.Scientific reports · 2018Article
- T1-Weighted Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to Distinguish Between Concurrent Cholesterol Granuloma and Invasive Ductal Carcinoma of the Breast: A Case Report.The American journal of case reports · 2018Article
- Comparison of strain and shear wave elastography for qualitative and quantitative assessment of breast masses in the same population.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe aimed to determine the correlations between the elasticity values of solid breast masses and histopathological findings to define cutoff elasticity values differentiating malignant from benign lesions. MATERIALS AND
methodsA total of 115 solid breast lesions of 109 consecutive patients were evaluated prospectively using shear wave elastography (SWE). Two orthogonal elastographic images of each lesion were obtained. Minimum, mean, and maximum elasticity values were calculated in regions of interest placed over the stiffest areas on the two images; we also calculated mass/fat elasticity ratios. Correlation of elastographic measurements with histopathological results were studied.
resultsEighty-three benign and thirty-two malignant lesions were histopathologically diagnosed. The minimum, mean, and maximum elasticity values, and the mass/fat elasticity ratios of malignant lesions, were significantly higher than those of benign lesions. The cutoff value was 45.7 kPa for mean elasticity (sensitivity, 96%; specificity, 95%), 54.3 kPa for maximum elasticity (sensitivity, 95%; specificity, 94%), 37.1 kPa for minimum elasticity (sensitivity, 96%; specificity, 95%), and 4.6 for the mass/fat elasticity ratio (sensitivity, 97%; specificity, 95%).
conclusionSWE yields additional valuable quantitative data to ultrasonographic examination on solid breast lesions. SWE may serve as a complementary tool for diagnosis of breast lesions. Long-term clinical studies are required to accurately select lesions requiring biopsy.
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