Evidence map›Paper›PMID 24508931›Full record

ArticleAmerican journal of physical medicine & rehabilitation2014

Computed tomography-based muscle attenuation and electrical impedance myography as indicators of trunk muscle strength independent of muscle size in older adults.

Dennis E Anderson, Jonathan F Bean, Nicole E Holt, John C Keel, Mary L Bouxsein

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in American journal of physical medicine & rehabilitation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05190289 (The Relationship Between Paraspinal Muscle Degeneration and Bone Mass and Clinical Outcomes After Surgery in Patients With Lumbar Degenerative Diseases), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05190289 unknown statusnot on this mapstarted 2021, after this paper: background citation

The Relationship Between Paraspinal Muscle Degeneration and Bone Mass and Clinical Outcomes After Surgery in Patients With Lumbar Degenerative Diseases

TypeobservationalSponsorPeking University Third HospitalRan2021 to 2022Enrolled600ConditionsDegenerative Lumbar Spinal Stenosis, Degenerative ScoliosisArmsPre-existing degenerative factors of paraspinal muscles and bone mass
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 29 citations in OpenAlex.

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  12. A Longitudinal Study of Trunk Muscle Properties and Severity of Thoracic Kyphosis in Women and Men: The Framingham Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
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  17. Estimating apparent maximum muscle stress of trunk extensor muscles in older adults using subject-specific musculoskeletal models.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Dennis E AndersonFrom the Department of Orthopedics, Beth Israel Deaconess Medical Center, Boston, Massachusetts (DEA, JCK, MLB); Department of Orthopedic Surgery, Harvard Medical School, Boston, Massachusetts (DEA, MLB); Spaulding Rehabilitation Hospital, Boston, Massachusetts (JFB, NEH); Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, Massachusetts (JFB, JCK); and The Spine Center, New England Baptist Hospital, Boston, Massachusetts (JCK).
Jonathan F Bean
Nicole E Holt
John C Keel
Mary L Bouxsein
Major League Baseball · USBeth Israel Deaconess Medical Center · USHarvard University · USSpaulding Rehabilitation Hospital · US

Funding

Translational Researchin Aging Trainnig ProgramT32AG023480 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI LIPSITZ, LEWIS · 2004 to 2024
$7.6M
Biomechanics of Vertebral Fracture: The Framingham QCT StudyR01AR053986 · NIAMS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BOUXSEIN, MARY L · 2007 to 2016
$5.4M
Developing Rehabilitative Strategies for Disability Prevention in Primary CareR01AG032052 · NIA · SPAULDING REHABILITATION HOSPITAL · PI BEAN, JONATHAN F · 2009 to 2013
$3.2M
A Research Mentoring Program in the Rehabilitative Care of Older AdultsK24HD070966 · NICHD · SPAULDING REHABILITATION HOSPITAL · PI BEAN, JONATHAN F · 2012 to 2016
$793k
NIAMS NIH HHS R01 AR053986NIAMS NIH HHS R01-AR053986NIA NIH HHS R01 AG032052NIA NIH HHS R01-AG032052NIA NIH HHS T32 AG023480NIA NIH HHS T32-AG023480NICHD NIH HHS K24 HD070966NICHD NIH HHS K24-HD070966
6 · The paper itself

Abstract

objectiveThe aim of this study was to examine the associations of computed tomography-based x-ray attenuation and paraspinal electrical impedance myography measures of trunk muscles with absolute and relative (normalized by body weight) trunk extension strength, independent of muscle cross-sectional area.

designThis is a cross-sectional study of mobility-limited community-dwelling older adults (34 women, 15 men; mean [SD] age, 78.2 [7.2] yrs) recruited from within an existing prospective research cohort. Trunk extension strength, computed tomography-based trunk muscle cross-sectional area and attenuation at L4 level, and paraspinal electrical impedance myography measures were collected.

resultsAttenuation was positively correlated with absolute and relative strength for multiple muscle groups (r = 0.32-0.61, P < 0.05). Paraspinal electrical impedance myography phase was positively correlated with paraspinal attenuation (r = 0.30, P = 0.039) and with relative strength (r = 0.30, P = 0.042). In multivariable linear regressions adjusting for sex and cross-sectional area, attenuations of the anterior abdominal muscles (semipartial r = 0.11, P = 0.013) and combined muscles (semipartial r = 0.07, P = 0.046) were associated with relative strength.

conclusionsAlthough attenuation was associated with relative strength, small effect sizes indicate limited usefulness as clinical measures of muscle strength independent of muscle size. However, there remains a need for additional studies in larger and more diverse groups of subjects.

Indexed as

Abdominal MusclesAgedAnatomy, Cross-SectionalCohort StudiesCross-Sectional StudiesElectric ImpedanceFemaleHumansMaleMultidetector Computed TomographyMultivariate AnalysisMuscle StrengthMyographyParaspinal MusclesPilot ProjectsSex Factors

Identifiers

PMID24508931
PMCPMC4105177
OpenAlexW2043924851

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.