Evidence map›Paper›PMID 24508736›Full record

ReviewExercise and sport sciences reviews2014

The emerging biomolecular role of vitamin D in skeletal muscle.

Rachele M Pojednic, Lisa Ceglia

Abstract readReview
In one paragraph

Review in Exercise and sport sciences reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  3. Frontiers in physiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rachele M Pojednic1Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University; 2Division of Endocrinology, Diabetes and Metabolism, Tufts Medical Center; and 3Bone Metabolism Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA.
Lisa Ceglia

Funding

Nutrition &Cardiovascular Disease Training ProgramT32HL069772 · NHLBI · TUFTS UNIVERSITY BOSTON · PI LICHTENSTEIN, ALICE H · 2003 to 2017
$2.1M
NHLBI NIH HHS T32 HL069772NHLBI NIH HHS T32HL69772
6 · The paper itself

Abstract

In this review, we summarize current evidence for a direct effect of vitamin D on skeletal muscle. A number of studies identify the receptor for 1,25-dihydroxyvitamin-D3 (vitamin D receptor (VDR)) and the enzyme CYP27B1 (1-α-hydroxylase) in muscle. We hypothesize that vitamin D acts on myocytes via the VDR, and we examine proposed effects on myocyte proliferation, differentiation, growth, and inflammation.

Indexed as

25-Hydroxyvitamin D3 1-alpha-HydroxylaseAnimalsCell DifferentiationCell ProliferationHumansMuscle CellsMuscle ContractionMuscle, SkeletalReceptors, CalcitriolVitamin D25-Hydroxyvitamin D3 1-alpha-HydroxylaseReceptors, CalcitriolVitamin D

Identifiers

PMID24508736
PMCPMC4369924

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.