Evidence map›Paper›PMID 24508648›Full record

Trial reportNeuroImage2014

Inter- and intra-individual variability in alpha peak frequency.

Saskia Haegens, Helena Cousijn, George Wallis, Paul J Harrison, Anna C Nobre

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in NeuroImage, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 273 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
273citing papers in PubMed, 3 pooled it
12.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

273 citing papers in PubMed, 3 syntheses or guidelines pooled it, 645 citations in OpenAlex.

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213 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Saskia HaegensDepartment of Psychiatry, Columbia University College of Physicians and Surgeons, New York, USA; Cognitive Neuroscience and Schizophrenia Program, Nathan Kline Institute, Orangeburg, USA. Electronic address: shaegens@gmail.com.
Helena CousijnDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK; Oxford Centre for Human Brain Activity, University of Oxford, Oxford, UK.
George WallisOxford Centre for Human Brain Activity, University of Oxford, Oxford, UK; Department of Experimental Psychology, University of Oxford, Oxford, UK.
Paul J HarrisonDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Anna C NobreOxford Centre for Human Brain Activity, University of Oxford, Oxford, UK; Department of Experimental Psychology, University of Oxford, Oxford, UK.
University of Oxford · GBColumbia University · USWarneford Hospital · GBWellcome Centre for Integrative Neuroimaging · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Converging electrophysiological evidence suggests that the alpha rhythm plays an important and active role in cognitive processing. Here, we systematically studied variability in posterior alpha peak frequency both between and within subjects. We recorded brain activity using MEG in 51 healthy human subjects under three experimental conditions - rest, passive visual stimulation and an N-back working memory paradigm, using source reconstruction methods to separate alpha activity from parietal and occipital sources. We asked how alpha peak frequency differed within subjects across cognitive conditions and regions of interest, and looked at the distribution of alpha peak frequency between subjects. In both regions we observed an increase of alpha peak frequency from resting state and passive visual stimulation conditions to the N-back paradigm, with a significantly higher alpha peak frequency in the 2-back compared to the 0-back condition. There was a trend for a greater increase in alpha peak frequency during the N-back task in the occipital vs. parietal cortex. The average alpha peak frequency across all subjects, conditions, and regions of interest was 10.3 Hz with a within-subject SD of 0.9 Hz and a between-subject SD of 2.8 Hz. We also measured beta peak frequencies, and except in the parietal cortex during rest, found no indication of a strictly harmonic relationship with alpha peak frequencies. We conclude that alpha peak frequency in posterior regions increases with increasing cognitive demands, and that the alpha rhythm operates across a wider frequency range than the 8-12 Hz band many studies tend to include in their analysis. Thus, using a fixed and limited alpha frequency band might bias results against certain subjects and conditions.

Indexed as

MagnetoencephalographyAdultAlpha RhythmBrain MappingBrain WavesCognitive ReserveExecutive FunctionFemaleHumansMaleOscillometryReproducibility of ResultsSensitivity and SpecificityYoung AdultAlphaBetaMEGOscillations

Identifiers

PMID24508648
PMCPMC4013551
OpenAlexW1979330140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.