Evidence map›Paper›PMID 24508350›Full record

ArticleClinical lymphoma, myeloma & leukemia2014

Poorer prognosis of African-American patients with mycosis fungoides: an analysis of the SEER dataset, 1988 to 2008.

Sameer K Nath, James B Yu, Lynn D Wilson

Open access · greenAbstract readComparative Study
In one paragraph

Article in Clinical lymphoma, myeloma & leukemia, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Skin Cancer in People of Color: A Systematic Review.American journal of clinical dermatology · 2022
    Pooled it
  2. Interventions for mycosis fungoides.The Cochrane database of systematic reviews · 2020
    Pooled it
  3. Article
  4. Recent trends of incidence and mortality of cutaneous lymphomas in Germany.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026
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  16. The impact of gender, age, race/ethnicity, and stage on quality of life in a spectrum of cutaneous lymphomas.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sameer K NathDepartment of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT.
James B YuDepartment of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT; Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT.
Lynn D WilsonDepartment of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT; Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT. Electronic address: Lynn.wilson@yale.edu.
Yale University · USYale Cancer Center · US

Funding

Yale University Clinical and Translational Science Award ProgramUL1TR000142 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$31.8M
Racial Disparities in Clinical Outcomes and the Therapeutic Use of Radiotherapy fR03CA151153 · NCI · YALE UNIVERSITY · PI WILSON, LYNN D · 2010 to 2010
$83k
NCATS NIH HHS UL1 TR000142NCI NIH HHS 1R03CA151153-01NCI NIH HHS R03 CA151153
6 · The paper itself

Abstract

backgroundThe aims of this study were: (1) to determine whether AA patients with MF have a worse prognosis despite accounting for varying clinical factors at presentation, and (2) to assess whether a racial disparity exists regarding utilization of radiation therapy (RT) as an initial treatment modality. MATERIALS AND

methodsThe SEER 1988-2008 public use database was investigated. Univariate and multivariate analysis was used to assess for factors significantly associated with disease-specific survival (DSS), overall survival (OS), and RT utilization survival.

resultsA total of 4892 patients with MF were identified with a median follow-up of 58 months. On multivariate analysis including tumor registry, age, sex, marital status, and tumor stage, AA race was significantly correlated with a worse OS (hazard ratio [HR], 1.58; P < .001) and DSS (HR, 1.78; P < .001). With regard to RT utilization, more advanced age (odds ratio [OR], 1.005; P < .001) and higher stage (OR, 3.03; P < .001) were associated with a higher likelihood of receiving RT, whereas female sex (OR, 0.81; P = .03) was associated with a lower likelihood of receiving RT. AA race was not significantly associated with RT utilization (P = .58).

conclusionAA race was associated with poorer survival despite accounting for demographic factors and tumor stage. Differences in RT utilization according to AA race were not found, however RT was less utilized for female patients. The etiology of this poorer prognosis is unclear and might be related to access to medical care, socioeconomic factors, or undetermined biological differences.

Indexed as

AdultAgedAge FactorsAsianBlack or African AmericanFemaleHealthcare DisparitiesHumansIncidenceMaleMarital StatusMiddle AgedMycosis FungoidesPrognosisRadiotherapySEER ProgramCutaneousPrognosisRaceRadiation utilizationSurvival

Identifiers

PMID24508350
PMCPMC4081527
OpenAlexW2028708191

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.