Evidence map›Paper›PMID 24506879›Full record

ArticleCell stem cell2014

Girl power: estrogen promotes HSC self-renewal.

Esther Carreras, Susan Kovats

Abstract readComment
In one paragraph

Article in Cell stem cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Esther CarrerasImmune Receptors of the Innate and Adaptive System Team, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Centre Esther Koplovitz, Rosselló, 149-153, 08036 Barcelona, Spain.
Susan KovatsArthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, 825 NE 13(th) Street, Oklahoma City, OK 73104, USA. Electronic address: susan-kovats@omrf.org.

Funding

Regulation of dendritic cells by estrogen receptors during influenza infectionR21AI092511 · NIAID · OKLAHOMA MEDICAL RESEARCH FOUNDATION · PI KOVATS, SUSAN · 2011 to 2012
$448k
NIAID NIH HHS NIH AI92511NIAID NIH HHS R21 AI092511
6 · The paper itself

Abstract

Although some hematopoietic cell types are known to respond to sex hormones, hematopoietic stem cells (HSCs) are generally thought to function similarly in both sexes. Recently in Nature, Nakada et al. (2014) show that HSCs respond to higher levels of estrogen in females, resulting in enhanced self-renewal and increased erythropoiesis.

Indexed as

AnimalsEstrogensFemaleHematopoietic Stem CellsMalePregnancyEstrogens

Identifiers

PMID24506879
PMCPMC3974548

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.