ArticlePloS one2014
The Brassicaceae-specific EWR1 gene provides resistance to vascular wilt pathogens.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 36 citations in OpenAlex.
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- Subtilase-mediated biogenesis of the expanded family of SERINE RICH ENDOGENOUS PEPTIDES.Nature plants · 2023Article
- Tissue-Specific Hormone Signalling and Defence Gene Induction in an In Vitro Assembly of the RapeseedInternational journal of molecular sciences · 2023Article
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- The Arabidopsis thaliana-Fusarium oxysporum strain 5176 pathosystem: an overview.Journal of experimental botany · 2022Review
- Research Advances and Prospects of Orphan Genes in Plants.Frontiers in plant science · 2022Review
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- Analysis of a gene family for PDF-like peptides from Arabidopsis.Scientific reports · 2021Article
- A novel motif in the 5'-UTR of an orphan gene 'Big Root Biomass' modulates root biomass in sesame.Plant biotechnology journal · 2021Article
- Taxonomically Restricted Wheat Genes Interact With Small Secreted Fungal Proteins and Enhance Resistance to Septoria Tritici Blotch Disease.Frontiers in plant science · 2020Article
- De novo assembly and discovery of genes involved in the response ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2019Article
- Mining ofInternational journal of molecular sciences · 2018Article
- Verticillium longisporum, the invisible threat to oilseed rape and other brassicaceous plant hosts.Molecular plant pathology · 2016Review
- TaFROG Encodes a Pooideae Orphan Protein That Interacts with SnRK1 and Enhances Resistance to the Mycotoxigenic Fungus Fusarium graminearum.Plant physiology · 2015Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Soil-borne vascular wilt diseases caused by Verticillium spp. are among the most destructive diseases worldwide in a wide range of plant species. The most effective means of controlling Verticillium wilt diseases is the use of genetic resistance. We have previously reported the identification of four activation-tagged Arabidopsis mutants which showed enhanced resistance to Verticillium wilt. Among these, one mutant also showed enhanced resistance to Ralstonia solanacearum, a bacterial vascular wilt pathogen. Cloning of the activation tag revealed an insertion upstream of gene At3g13437, which we designated as EWR1 (for Enhancer of vascular Wilt Resistance 1) that encodes a putatively secreted protein of unknown function. The search for homologs of Arabidopsis EWR1 (AtEWR1) in public databases only identified homologs within the Brassicaceae family. We subsequently cloned the EWR1 homolog from Brassica oleracea (BoEWR1) and show that over-expression in Arabidopsis results in V. dahliae resistance. Moreover, over-expression of AtEWR1 and BoEWR1 in N. benthamiana, a member of the Solanaceae family, results in V. dahliae resistance, suggesting that EWR1 homologs can be used to engineer Verticillium wilt resistance in non-Brassicaceae crops as well.
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