Evidence map›Paper›PMID 24505429›Full record

ArticlePloS one2014

Myocardial defect detection using PET-CT: phantom studies.

Eugene S Mananga, Georges El Fakhri, Joshua Schaefferkoetter, Ali A Bonab, Jinsong Ouyang

Abstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. The impact of the air pollution on health in New York City.Journal of public health research · 2023
    Review
  2. Article
  3. Comparative analysis of iterative reconstruction algorithms with resolution recovery and time of flight modeling forJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eugene S ManangaCenter for Advanced Medical Imaging Sciences, Division of Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital, Boston, Massachusetts, United States of America ; Department of Radiology, Harvard Medical School, Boston, Massachusetts, United States of America.
Georges El FakhriCenter for Advanced Medical Imaging Sciences, Division of Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital, Boston, Massachusetts, United States of America ; Department of Radiology, Harvard Medical School, Boston, Massachusetts, United States of America.
Joshua SchaefferkoetterASTAR-NUS Clinical Imaging and Research Centre (CIRC), Singapore, Singapore.
Ali A BonabCenter for Advanced Medical Imaging Sciences, Division of Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital, Boston, Massachusetts, United States of America ; Department of Radiology, Harvard Medical School, Boston, Massachusetts, United States of America.
Jinsong OuyangCenter for Advanced Medical Imaging Sciences, Division of Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital, Boston, Massachusetts, United States of America ; Department of Radiology, Harvard Medical School, Boston, Massachusetts, United States of America.

Funding

Quantitative Oncologic PET-MRR01CA165221 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI EL FAKHRI, GEORGES · 2012 to 2023
$4.7M
Postgraduate Training Program in Medical Imaging (PTPMI)T32EB013180 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Ciprian Catana, Pedram Heidari · 2011 to 2026
$3.7M
Quantitative Cardiac PETR01HL110241 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI EL FAKHRI, GEORGES · 2011 to 2014
$1.9M
NCI NIH HHS R01 CA165221NHLBI NIH HHS R01 HL110241NHLBI NIH HHS R01-HL110241NIBIB NIH HHS T32 EB013180NIBIB NIH HHS T32-EB013180
6 · The paper itself

Abstract

It is expected that both noise and activity distribution can have impact on the detectability of a myocardial defect in a cardiac PET study. In this work, we performed phantom studies to investigate the detectability of a defect in the myocardium for different noise levels and activity distributions. We evaluated the performance of three reconstruction schemes: Filtered Back-Projection (FBP), Ordinary Poisson Ordered Subset Expectation Maximization (OP-OSEM), and Point Spread Function corrected OSEM (PSF-OSEM). We used the Channelized Hotelling Observer (CHO) for the task of myocardial defect detection. We found that the detectability of a myocardial defect is almost entirely dependent on the noise level and the contrast between the defect and its surroundings.

Indexed as

AlgorithmsEquipment DesignFemaleHumansMaleMyocardiumPhantoms, ImagingPositron-Emission Tomography

Identifiers

PMID24505429
PMCPMC3914931

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.