ArticlePloS one2014
Relationships between reward sensitivity, risk-taking and family history of alcoholism during an interactive competitive fMRI task.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review of the Balloon Analogue Risk Task (BART) in Alcohol Research.Alcohol and alcoholism (Oxford, Oxfordshire) · 2022Pooled it
- Characteristics of Adolescents with and without a Family History of Substance Use Disorder from a Minority Cohort.Children (Basel, Switzerland) · 2024Article
- Neural Differences in Relation to Risk Preferences during Reward Processing: An Event-Related Potential Study.Brain sciences · 2023Article
- Fear and anxiety in the face of COVID-19: Negative dispositions towards risk and uncertainty as vulnerability factors.Journal of anxiety disorders · 2021Review
- Mapping data-driven individualized neurobehavioral phenotypes in heavy alcohol drinkers.Alcoholism, clinical and experimental research · 2021Article
- Brain responses during delay discounting in youth at high-risk for substance use disorders.NeuroImage. Clinical · 2021Article
- Prosody production networks are modulated by sensory cues and social context.Social cognitive and affective neuroscience · 2018Article
- Comparison of methods for detecting asymptomatic malaria infections in the China-Myanmar border area.Malaria journal · 2017Article
- A Preliminary Prospective Study of an Escalation in 'Maximum Daily Drinks', Fronto-Parietal Circuitry and Impulsivity-Related Domains in Young Adult Drinkers.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2016Article
- Neurobiological phenotypes associated with a family history of alcoholism.Drug and alcohol dependence · 2016Review
- Family history density of alcoholism relates to left nucleus accumbens volume in adolescent girls.Journal of studies on alcohol and drugs · 2015Article
- Neurophysiological Correlates and Differential Drug Response in Subjects With a Family History of an Alcohol Use Disorder.Chronic stress (Thousand Oaks, Calif.)Article
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Authors and funding
7 authors.
Funding
Abstract
backgroundIndividuals with a positive family history for alcoholism (FHP) have shown differences from family-history-negative (FHN) individuals in the neural correlates of reward processing. FHP, compared to FHN individuals, demonstrate relatively diminished ventral striatal activation during anticipation of monetary rewards, and the degree of ventral striatal activation shows an inverse correlation with specific impulsivity measures in alcohol-dependent individuals. Rewards in socially interactive contexts relate importantly to addictive propensities, yet have not been examined with respect to how their neural underpinnings relate to impulsivity-related measures. Here we describe impulsivity measures in FHN and FHP individuals as they relate to a socially interactive functional magnetic resonance imaging (fMRI) task.
methodsForty FHP and 29 FHN subjects without histories of Axis-I disorders completed a socially interactive Domino task during functional magnetic resonance imaging and completed self-report and behavioral impulsivity-related assessments.
resultsFHP compared to FHN individuals showed higher scores (p = .004) on one impulsivity-related factor relating to both compulsivity (Padua Inventory) and reward/punishment sensitivity (Sensitivity to Punishment/Sensitivity to Reward Questionnaire). Multiple regression analysis within a reward-related network revealed a correlation between risk-taking (involving another impulsivity-related factor, the Balloon Analog Risk Task (BART)) and right ventral striatum activation under reward >punishment contrast (p<0.05 FWE corrected) in the social task.
conclusionsBehavioral risk-taking scores may be more closely associated with neural correlates of reward responsiveness in socially interactive contexts than are FH status or impulsivity-related self-report measures. These findings suggest that risk-taking assessments be examined further in socially interactive settings relevant to addictive behaviors.
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