Trial reportPloS one2014
Objectively measured sedentary time is related to quality of life among cancer survivors.
Trial report in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- Interventions to Reduce Sedentary Behavior in Cancer Patients and Survivors: a Systematic Review.Current oncology reports · 2022Pooled it
- Survivorship: healthy lifestyles, version 2.2014.Journal of the National Comprehensive Cancer Network : JNCCN · 2014Guideline
- Fit4Surgery: A pilot randomized controlled trial to assess the feasibility of prehabilitation prior to debulking surgery for ovarian cancer.Gynecologic oncology · 2025Trial
- Feasibility and preliminary effects of the Fit2ThriveMB pilot physical activity promotion intervention on physical activity and patient reported outcomes in individuals with metastatic breast cancer.Breast cancer research and treatment · 2024Trial
- Impact on Health-Related Quality of Life after Different Aerobic Exercise Programs in Physically Inactive Adults with Overweight/Obesity and Primary Hypertension: Data from the EXERDIET-HTA Study.International journal of environmental research and public health · 2020Trial
- Effectiveness of a multicomponent exercise program in the attenuation of frailty in long-term nursing home residents: study protocol for a randomized clinical controlled trial.BMC geriatrics · 2017Trial
- Feasibility of Beans/Bran Enriching Nutritional Eating For Intestinal Health & Cancer Including Activity for Longevity: A Pilot Trial to Improve Healthy Lifestyles among Individuals at High Risk for Colorectal Cancer.Integrative cancer therapiesTrial
- The importance of meeting physical activity recommendations and limiting sedentary time in adult survivors of childhood acute lymphoblastic leukemia - associations with fatigue and HRQoL.Journal of cancer survivorship : research and practice · 2026Article
- An App-Based Behavioral Support Intervention Promoting Physical Activity (APPROACH) in Patients Diagnosed With Breast, Prostate, or Colorectal Cancer: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2026Article
- Sedentary behavior, physical activity, and health-related quality of life in adults with multiple sclerosis.Disability and rehabilitation · 2025Article
- Acceptability of the Fit2ThriveMB mHealth physical activity promotion intervention in women with metastatic breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Associations of physical activity and sedentary time with health-related quality of life in patients with localized renal cell cancer: a cross-sectional analysis within the ReLife study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Reallocating Time to Physical Activity and Sleep: Associations with Body Mass Index in Cancer Survivors.International journal of behavioral medicine · 2024Article
- A distance-based, randomized controlled trial for reducing sedentary behavior among prostate cancer survivors: a study protocol.BMC public health · 2022Article
- Health behaviors and well-being among those "living" with metastatic cancer in Alabama.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- The association between physical activity, sedentary time and health-related quality of life in cancer survivors.Health and quality of life outcomes · 2021Article
- Physical Activity, Sitting Time, and Quality of Life among Breast and Gynaecology Cancer Survivors.Asian Pacific journal of cancer prevention : APJCP · 2021Article
- A Technology-Based Physical Activity Intervention for Patients With Metastatic Breast Cancer (Fit2ThriveMB): Protocol for a Randomized Controlled Trial.JMIR research protocols · 2021Article
- A Home-Based Mobile Health Intervention to Replace Sedentary Time With Light Physical Activity in Older Cancer Survivors: Randomized Controlled Pilot Trial.JMIR cancer · 2021Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
purposeWhile exercise has been shown to be beneficial in improving health-related quality of life (HRQOL) among cancer survivors, evidence is limited on the independent role of sedentary behavior. We examined how objectively measured sedentary time was associated with HRQOL among long-term cancer survivors.
methodsThis cross-sectional study included 54 cancer survivors, on average 3.4 years postdiagnosis, who were enrolled into an exercise trial designed to improve cognitive function. At baseline, we measured sedentary time and moderate-vigorous intensity physical activity with the ActivPal, cardiorespiratory fitness with treadmill testing, and self-reported HRQOL with an established scale (SF-36). In multivariate models, we regressed HRQOL on sedentary time (percent of waking time spent sitting and lying).
resultsSurvivors with higher sedentary time had significantly poorer physical functioning (β = -0.50, p = 0.028), general health (β = -0.75, ptrend = 0.004), and physical summary scores (β = -0.34, p = 0.003). We did not observe associations between sedentary time and role-physical (p = 0.342), bodily-pain (p = 0.117), vitality (p = 0.095), social functioning (p = 0.407), role-emotional (p = 0.509), mental health (p = 0.494), or mental summary scores (p = 0.527).
conclusionIn this cross-sectional study of cancer survivors, we observed deleterious associations between sedentary time and aspects of physical HRQOL. Future prospective studies of sedentary time and HRQOL are needed to establish temporality and to facilitate the design of effective health promotion interventions for cancer survivors.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.